Document Type

Article

Publication Date

1-11-2017

NLM Title Abbreviation

Int J Womens Dermatol

Journal/Book/Conference Title

International Journal of Women's Dermatology

PubMed ID

28560302

DOI of Published Version

10.1016/j.ijwd.2016.11.003

Total Pages

5

Abstract

Localized cutaneous nodular amyloidosis (LCNA) is the rarest form of localized cutaneous amyloidosis. In patients with LCNA, local plasma cells secrete immunoglobulin light chains called amyloid L via an unknown mechanism. LCNA has been associated with autoimmune connective tissue diseases such as most commonly Sjögren syndrome. A few reported cases of LCNA are associated with limited systemic sclerosis (LSSc). We report three cases of LCNA in patients with LSSc to add to the existing literature, discuss the disease association and proposed pathophysiology, and briefly review the existing information in current literature. It is important to closely follow patients with LCNA to monitor progression to systemic amyloidosis.

Keywords

OAfund, nodular amyloidosis, limited systemic sclerosis, connective tissue disease, histopathology

Journal Article Version

Version of Record

Published Article/Book Citation

International Journal of Women's Dermatology 3 (2017) 91–95

https://doi.org/10.1016/j.ijwd.2016.11.003

Rights

Copyright (c) 2016 The Authors

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Included in

Dermatology Commons

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URL

http://ir.uiowa.edu/dermatology_pubs/5