Iowa Research Online

The Missing Link, Maria Noterman
Synthesis: A Digital Journal of Student Science Communication

Brains!: A Neuroscience Comic Book for Kids, Anya Kim
Synthesis: A Digital Journal of Student Science Communication

A New Class of Antibiotics Could Stop Drug-Resistant Bacteria in their Tracks, Nicholas McCarty
Synthesis: A Digital Journal of Student Science Communication

The Empathetic Scientist, Maria Noterman
Synthesis: A Digital Journal of Student Science Communication

Editors' Note, Lori Adams, Matthew J. Gilchrist, Brinda Shetty
Synthesis: A Digital Journal of Student Science Communication

Tadpole Startle (C-Start) Response Videos, Kasra Zarei, Karen Elliott, Sanam Zarei, Bernd Fritzsch, James Buchholz
Department of Mechanical and Industrial Engineering Publications

Neuroscience: What we don't know is the most exciting part, Kayleen Schreiber
Synthesis: A Digital Journal of Student Science Communication

Art as a Tool in Science Communication, Brittany Todd
Synthesis: A Digital Journal of Student Science Communication

Diabetes: A History, Nicholas McCarty
Synthesis: A Digital Journal of Student Science Communication

Inverse Relationship between Progesterone Receptor and Myc in Endometrial Cancer, Tamar Kavlashvili
University of Iowa Honors Theses

Intervention to Enhance the Use of Sit-Stand Desks in College Students, Ashley Raulli
University of Iowa Honors Theses

The Role of gpx-8 in DNA Repair of C. elegans, Grant T. Read
University of Iowa Honors Theses

Experimentation and quantitative feedback applied to the growth of Stemosphere: A student managed blog and social media platform., George Murray
Synthesis: A Digital Journal of Student Science Communication

Novel roles of staphylococcal proteases and cross talk in biofilm formation and virulence, Alexandra E. Paharik
Theses and Dissertations

Adoptive cancer immunotherapy with human Vγ2vδ2 T cells, Mohanad Hameed Nada
Theses and Dissertations

Graph theory analysis of single cell transcriptomes define islet signaling networks and cell identity, Scott Robert Tyler
Theses and Dissertations

Cortical spreading depression upregulates calcitonin gene-related peptide expression in the ipsilateral cerebral cortex, Anne Elizabeth Tye
Theses and Dissertations

Generating patient-specific induced pluripotent stem cell-derived choroirdal endothelium to study and treat macular degeneration, Allison Elaine Songstad
Theses and Dissertations

Novel tools for targeting PCBs and PCB metabolites using ssDNA aptamers, Marisa Genevive Salomon Beltran
Theses and Dissertations

Exposure to arsenic and atrazine from drinking water and risk of cancer, Taehyun Roh
Theses and Dissertations

Evaluating gene flow, gene expression divergence, and hybrid expression in Drosophila sister species, Danielle Kay Herrig
Theses and Dissertations

Goggatomy: A Method for Opening Small Cuticular Compartments in Arthropods for Physiological Experiments, Alan R. Kay, Davide Raccuglia, Jon Scholte, Elena Sivan-Loukianova, Christopher A. Barwacz, Steven R. Armstrong, C Allan Guymon, Michael N. Nitabach, Daniel F. Eberl
Department of Biology Publications

The roles of a unique G-protein coupled dual receptor for dopamine and steroids in neuronal physiology and behavior, Arianna Ruth Stini Lark
Theses and Dissertations

What role does effort play: the effect of effort for gesture interfaces and the effect of pointing on spatial working memory, Xiaoxing Liu
Theses and Dissertations

New roles for an old cytokine : characterizing how exposure to Il-12 alters human CD4 And CD8 T cell responses, Aldo Fabian Vacaflores Salinas
Theses and Dissertations

Genomic and phenotypic consequences of asexuality, Joel Sharbrough
Theses and Dissertations

Targeting unique oxidative metabolism of clonogenic multiple myeloma cells for therapy, Jeanine C. Schibler
Theses and Dissertations

The nature, extent, and consequences of polyglutamine tract variation in Notch in Drosophila, Clinton Rice
Theses and Dissertations

"The future of football is feminine" : a critical cultural history of the U.S. women's national soccer team, Eileen Marie Narcotta-Welp
Theses and Dissertations

Age differences in kinesthetic and static-position sense of the upper limb in unconstrained 3-D tasks, Christopher Ross Coffman
Theses and Dissertations

Environmental and genetic modifiers of Shudderer, a Drosophila voltage-gated sodium channel mutant, Hung-Lin Chen
Theses and Dissertations

Evaluation of alterations in dopamine and neuro-toxicity caused by co-exposure to lead (Pb) and polychlorinated biphenyls (PCBs), Sabah Hassain Enayah
Theses and Dissertations

A postsynaptic signaling system for the regulation of homeostatic synaptic plasticity, Ashlyn Spring
Theses and Dissertations

CD8 T cell dependent and independent immunity against Plasmodium following vaccination, Katherine Lee Doll Kanne
Theses and Dissertations

Prostaglandin regulation of immune responses against coronavirus infections, Rahul Vijay
Theses and Dissertations

Identification of bovel mechanisms mediating skeletal muscle atrophy, Daniel Kenneth Fox
Theses and Dissertations

The hippocampus and semantic memory beyond acquisition: a lesion study of hippocampal contributions to the maintenance, updating, and use of remote semantic memory, Nathaniel Bloem Klooster
Theses and Dissertations

Novel NAD+ metabolomic technologies and their applications to Nicotinamide Riboside interventions, Samuel A.J. Trammell
Theses and Dissertations

Time-dependent alterations in memory CD8 T cell function after infection, Matthew David Martin
Theses and Dissertations

Afferent vs. efferent cervical vagal nerve stimulation: effects on blood glucose, insulin, and glucagon concentrations in rats, Erin Elizabeth Meyers
Theses and Dissertations

Fronto-striatal circuitry in children at risk for Huntington's disease, Qyong Lee
Theses and Dissertations

The vertical jump test as a health promotion screening tool for predicting bone strength in young adults, Maggie Marie King
Theses and Dissertations

Optimizing motor Mmemory in healthy adults, Sara Jeanne Hussain
Theses and Dissertations

Pre-mating reproductive isolation between three sympatric varieties of a specialist insect, Alaine Constance Hippee
Theses and Dissertations

Examining the effects of reward and punishment on incidental learning, Michael Vincent Freedberg
Theses and Dissertations

Identification and characterization of transcriptional enhancers integrating Notch and other developmental signals : regulation of the Drosophila nab locus, Elizabeth Kristine Stroebele
Theses and Dissertations

Inhibition of peroxide removal systems and ascorbate-induced cytotoxicity in pancreatic cancer, Hannah Van Beek
Theses and Dissertations

Mitochondrial calcium uniporter is a nodal regulator of physiological and pathological stress responses in myocardium, Tyler Paul Rasmussen
Theses and Dissertations

Oxidative stress resistance in the Francisella tularensis live vaccine strain is associated with genetic variability in the ferrous iron uptake gene feoB, Joshua Robert Fletcher
Theses and Dissertations

Exploring the genetics of a complex disease - atypical hemolytic uremic syndrome, Fengxiao Bu
Theses and Dissertations

The molecular pathogenesis of skeletal muscle atrophy, Kale Stephen Bongers
Theses and Dissertations

Role of anxiety on vascular dysfunction, Tiwaloluwa Adedamola Ajibewa
Theses and Dissertations

Assessment of hepatic micronutrient disruption and the hepatotoxicity of 3,3',4,4',5-pentachlorobiphenyl (PCB126), William Delbert Klaren
Theses and Dissertations

Serotonin neurons maintain central mechanisms regulating metabolic homeostasis and are vital to thermogenic activation, Jacob McGlashon
Theses and Dissertations

PCB126-induced metabolic disruption: effects on liver metabolism and adipocyte development, Gopi Srinivas Gadupudi
Theses and Dissertations

Neutrophil responses to infection with leishmania parasites: MHC class II-expression and parasite life-stage interactions, Richard Elliot Davis
Theses and Dissertations

Whole exome analysis of individuals and families with chronic recurrent multifocal osteomyelitis (CRMO), Allison Jeanne Cox
Theses and Dissertations

The brain renin-angiotensin system in metabolic and cardiovascular regulation, Kristin Elizabeth Claflin
Theses and Dissertations

Dear Bees, I love you., Dakota Keller
University of Iowa Honors Theses

5-HT Neurons and CO₂ chemoreception: effects of anesthetics, development, and genetic background, Cory Allen Massey
Theses and Dissertations

Tissue-specific roles for the renin-angiotensin system in cardiovascular and metabolic regulation, Nicole Kathryn Littlejohn
Theses and Dissertations

Plasticity and reorganization of brain networks subserving emotion and decision-making, Matthew James Sutterer
Theses and Dissertations

Branching out by sticking together: elucidating mechanisms of gamma-protocadherin control of dendrite arborization, Austin Byler Keeler
Theses and Dissertations

Fine scale recombination variation in Drosophila melanogaster, Andrew B. Adrian
Theses and Dissertations

Effects of polychlorinated biphenyls (PCBs) on telomere maintenance in hematopoietic stem cells and progenitor cells, Xing Xin
Theses and Dissertations

Secreted Staphylococcus aureus virulence factors and their role in chronic wound development and persistence, Joseph Alan Merriman
Theses and Dissertations

Protein adducts and crosslinking by reactive metabolites of polychlorinated biphenyls (PCBs), Miao Li
Theses and Dissertations

Dab2 plays a role in the post-endocytic trafficking of VEGFR2, Shivangi Makarand Inamdar
Theses and Dissertations

Validation of electrostatic dust collectors (EDCs) as effective passive samplers, Brita Jane Kilburg-Basnyat
Theses and Dissertations

Dynamic characteristics of emotion and effects of emotion on driving in normal aging and Parkinson’s disease, Kuan-Hua Chen
Theses and Dissertations

The role of BST-2/Tetherin in host protection and disease manifestation, Wadie D. Mahauad-Fernandez, Chioma M. Okeoma
Department of Microbiology Publications

Characterization of risperidone-induced weight gain mediated by alterations of the gut microbiome and suppression of host energy expenditure, Sarah Bahr
Theses and Dissertations

Ion pumps in Drosophila hearing, Betul Zora
Theses and Dissertations

Characterization of ExsA self-association and DNA-binding as therapeutic targets to prevent expression of the Pseudomonas aeruginosa type III secretion system, Anne Elizabeth Marsden
Theses and Dissertations

Acceptability and efficacy of a low intensity family-based weight loss intervention, Roberto Martín Benzo
Theses and Dissertations

Exodus of champions : the great migration and the shaping of the civil rights activities of Floyd Patterson, Sonny Liston, Joe Frazier and George Foreman, Daniel Lawrence Taradash
Theses and Dissertations

Characterizing the role of the enterotoxin gene cluster in Staphylococcus aureus diseases, Christopher Stach
Theses and Dissertations

The generation and differentiation of memory CD8 T cell responses in health and disease, Shaniya H. Khan
Theses and Dissertations

Dual roles for an intracellular calcium-signaling pathway in regulating synaptic homeostasis and neuronal excitability, Douglas J. Brusich
Theses and Dissertations

Coevolution of Rhagoletis hosts and their parasitic wasps, Gabriela Hamerlinck
Theses and Dissertations

Exosomes: Implications in HIV-1 Pathogenesis, Marisa N. Madison, Chioma M. Okeoma
Department of Microbiology Publications

Transient and Stable Transformation of Ceratopteris Richardii Gametophytes., Linh T. Bui, Angela Ruth Cordle, Erin E. Irish, Chi-Lien Cheng
Department of Biology Publications

Ferret: A Sentence-based Literature Scanning System, Padmini Srinivasan, Xiao-Ning Zhang, Roxane Bouten, Caren Chang
Department of Computer Science Publications

Molecular investigations of age-related macular degeneration, Steven Scott Whitmore
Theses and Dissertations

Novel regulation and function of the actin bundling protein Fascin, Christopher Michael Groen
Theses and Dissertations

G-protein coupled receptor expression patterns in medulloblastoma subgroups: identifying and exploiting molecular targets, Kelsey Lynnea Whittier
Theses and Dissertations

Evaluation of a modified paleolithic dietary intervention for the treatment of relapsing-remitting multiple sclerosis, Amanda Kay Irish
Theses and Dissertations

The role of the GRB2 family of adaptor proteins in T cell receptor-mediated signaling, Mahmood Bilal
Theses and Dissertations

Role of aging and aerobic fitness on large elastic artery stiffness, brain structure and cognitive performance in humans, Lyndsey Elisabeth DuBose
Theses and Dissertations

The impact of robust memory T cell responses against respiratory syncytial virus, Cory James Knudson
Theses and Dissertations

The role of the striatum in impulsivity and self-awareness : neuropsychological and functional neuroimaging approaches, Natassia Veranya Gaznick
Theses and Dissertations

An investigation of the molecular and biophysical properties of metastatic cells, Jones Trevor Nauseef
Theses and Dissertations

Effects and regulation of dystroglycan glycosylation in cancer, Michael Raymond Miller
Theses and Dissertations

Systems-based discovery of tomatidine as a small molecule inhibitor of skeletal muscle atrophy, Michael Christopher Dyle
Theses and Dissertations

Molecular mechanisms of the anti-cancer action of schweinfurthins, Chaoqun Zheng
Theses and Dissertations

Molecular regulation of Nox1 NADPH oxidase in vascular smooth muscle cell activation, Jennifer Lee Streeter
Theses and Dissertations

Novel roles for TCF-1 and LEF-1 in directing CD4+ T cell fate and silencing CD4 in CD8+ T cells, Farrah Christine Steinke
Theses and Dissertations

Investigation and application of novel adeno-associated viral vectors for cystic fibrosis gene therapy, Benjamin Richard Steines
Theses and Dissertations

Mechanisms of the anti-proliferative actions of the schweinfurthins in cancer cells, Ryan Michael Sheehy
Theses and Dissertations

Evolution of meiosis genes in sexual vs. asexual Potamopyrgus antipodarum, Christopher Steven Rice
Theses and Dissertations

NIAM, a novel activator of p53 and potential tumor suppressor, Sara Marie Reed
Theses and Dissertations

Targeting membrane proteins to inner segments of vertebrate photoreceptors, Yuan Pan
Theses and Dissertations

Ecological and biogeographical patterns associated with genetic differentiation in a diverse genus of Neotropical fruit flies, Kristina Jane Ottens
Theses and Dissertations

Impacts of urban versus agricultural landcover on spatial distributions and trophic interactions among specialist insects, Amanda Erin Nelson
Theses and Dissertations

The effects of stress on decision making and the prefrontal cortex among older adults, Georgina Laurybel Moreno
Theses and Dissertations

TRAF3 regulates B cell survival and IL-6 receptor signaling, Wai Wai Lin
Theses and Dissertations

Effects of polyploidy and reproductive mode on life history trait expression, Katelyn Larkin
Theses and Dissertations

Examining the role of ASIC1A in mouse models of addiction and CO2-evoked panic-like behaviors, Collin John Kreple
Theses and Dissertations

Global regulation of the Pseudomonas aeruginosa type III secretion system, Peter J. Intile
Theses and Dissertations

Regulation of vascular function: roles for Cullin-3 and RhoBTB1 In Pparγ-mediated blood pressure control, Stella-Rita C. Ibeawuchi
Theses and Dissertations

Molecular genetics of optic nerve disease using patients with cavitary optic disc anomaly, Ralph Jeremiah Hazlewood II
Theses and Dissertations

Emotion and decision-making in the aging brain, Kameko Mae Halfmann
Theses and Dissertations

Why it hurts to exercise: a study of sex, acid sensing ion channels, and fatigue metabolites in the onset of muscle pain, Nicholas Scott Gregory
Theses and Dissertations

Molecular mechanisms of brain-ras hyperactivity upon fluid balance, and sufficiency of angiotensin production from the subfornical organ to affect fluid balance, Jeffrey Coble
Theses and Dissertations

Tropism of human pegivirus (formerly known as GB virus C) and host immunomodulation : insights into viral persistence, Ernest Tafara Chivero
Theses and Dissertations

A neuropsychological investigation of music, emotion, and autobiographical memory, Amy Meredith Belfi
Theses and Dissertations

The Justy mutation disrupts the regulation of gene expression and cell cycle progression during B lymphopoiesis, Jennifer Yamaoka Barr
Theses and Dissertations

Effects of Transcranial Direct Current Stimulation on the Control of Finger Force during Dexterous Manipulation in Healthy Older Adults, Pranav J. Parikh, Kelly J. Cole
Department of Health and Human Physiology Publications

Bone Marrow Stromal Antigen 2 (BST-2) DNA Is Demethylated in Breast Tumors and Breast Cancer Cells, Wadie D. Mahauad-Fernandez, Nicholas C. Borcherding, Weizhou Zhang, Chioma M. Okeoma
Department of Microbiology Publications

Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation, Jennifer Kersigo, Bernd Fritzsch
Department of Biology Publications

Childhood-onset schizophrenia case with 2.2 Mb deletion at chromosome 3p12.2-p12.1 and two large chromosomal abnormalities at 16q22.3-q24.3 and Xq23-q28, Danielle Rudd, Michael Axelsen, Eric A. Epping, Nancy Andreasen, Thomas Wassink
Interdisciplinary Program in Genetics Publications

The role of cAMP in synaptic homeostasis in response to environmental temperature challenges and hyperexcitability mutations, Atsushi Ueda, Chun-Fang Wu
Department of Biology Publications

Wnt signaling and β-catenin regulation during asymmetric cell division in Caenorhabditis elegans, Austin Thomas Baldwin
Theses and Dissertations

The role of viral strain in a congenital brain infection, Jeffrey Michael Plume
Theses and Dissertations

Dissection of molecular interactions of replication protein A in replication and repair, Ran Chen
Theses and Dissertations

Systematic analysis of enhancer and promoter interactions, Bing He
Theses and Dissertations

Neuroprotective strategies for traumatic brain injury, Terry Yin
Theses and Dissertations

A tale of two genes controlling behavior in Drosophila: role of DopEcR in ethanol-induced behavior and effects of epilepsy mutations on sleep, Emily Kay Petruccelli
Theses and Dissertations

Language and reading dysfunction in boys with isolated cleft lip and/or palate : a relationship to abnormal structural and functional connectivity in the brain, Ian John DeVolder
Theses and Dissertations

Airway surface liquid antiviral activity in cystic fibrosis, Abigail Rae Berkebile
Theses and Dissertations

Uncontrolled Combustion of Shredded Tires in a Landfill - Part 2: Population Exposure, Public Health Response, and an Air Quality Index for Urban Fires, Ashish Singh, Scott N. Spak, Elizabeth A. Stone, Jared Downard, Robert L. Bullard, Mark Pooley, Pamela A. Kostle, Matthew W. Mainprize, Michael D. Wichman, Thomas M. Peters, Douglas Beardsley, Charles O. Stanier
Department of Chemical and Biochemical Engineering Publications

Yellow Pacific on White ice : transnational, postcolonial and genealogical reading of Asian American and Asian female figure skaters in the US media, Jae Chul Seo
Theses and Dissertations

The role of protein geranylgeranylation in prostate cancer, Jacqueline Erin Reilly
Theses and Dissertations

Metabolic oxidative stress, selenoprotein P, and cellular response to PCB3-quinone exposure, Wusheng Xiao
Theses and Dissertations

Biodegradable microparticles for in situ immunization against cancer, Amani Riad Makkouk
Theses and Dissertations

The role of AIM2 and NLRP12 in the innate immune response to Francisella tularensis, Tyler Kent Ulland
Theses and Dissertations

Pharmacological and biophysical characterization of a prokaryotic voltage-gated sodium channel, So Ra Lee
Theses and Dissertations

Computational methods for identification of disease-associated variations in exome sequencing, Alex Handler Wagner
Theses and Dissertations

Genetic and functional analysis of synaptic CA²⁺ dynamics in Drosophila, Xiaomin Xing
Theses and Dissertations

Proposed mechanisms underlining the potential effects of Staphylococcal superantigens on the development of type two diabetes, Bao Gia Vu
Theses and Dissertations

Pulmonary dendritic cells and CD8 T cells facilitate protection following influenza A virus vaccination and infection, Emily Ann Hemann
Theses and Dissertations

Coarse grained potential functions for proteins derived from all-atom explicit-solvent molecular dynamics simulations, Casey Tyler Andrews
Theses and Dissertations

Copper-zinc superoxide dismutase and glucose metabolism as redox targets for bortezomib resistance in multiple myeloma, Kelley Salem
Theses and Dissertations

The tumor microenvironment is critical for the development of plasma cell neoplasia in mice, Timothy Robert Rosean
Theses and Dissertations

Mechanisms of vascular disease: divergent roles for suppressor of cytokine signaling 3 in angiotensin II-induced vascular dysfunction, Ying Li
Theses and Dissertations

A framework for emerging topic detection in biomedicine, Charisse Renee Madlock-Brown
Theses and Dissertations

Effect of aging and habitual aerobic exercise on endothelial function, arterial stiffness, and autonomic function in humans, Stephen Alan Harris
Theses and Dissertations

Molecular and cellular basis of hematopoietic stem cells maintenance and differentiation, Khanh Linh Duong
Theses and Dissertations

Dynamics of gene expression during vegetative phase change in maize, Benjamin DuPree Beydler
Theses and Dissertations

Bone marrow stromal antigen 2 expressed in cancer cells promotes mammary tumor growth and metastasis, Wadie D. Mahauad-Fernandez, Kris A. DeMali, Alicia K. Olivier, Chioma M. Okeoma
Department of Microbiology Publications

Testing Genetic Association by Regressing Genotype over Multiple Phenotypes, Kai Wang
Department of Biostatistics Publications

Defining the role of the nuclear lamina LEM Domain protein Otefin in germline stem cells, Lacy Jo Barton
Theses and Dissertations

The characterization of clinical, genetic and molecular aspects of primary angle closure glaucoma in a canine genetic model, Dina Ahram
Theses and Dissertations

A role for the CSN/COP9 signalosome in synaptonemal complex assembly and meiotic progression, Heather Marie Brockway
Theses and Dissertations

Identification and characterization of capsule and/or O-antigen mutants of Francisella tularensis Schu S4, Jed Anthony Rasmussen
Theses and Dissertations

Intrinsic and extrinsic regulation of DNA methylation during malignant transformation, Bo-Kuan Wu
Theses and Dissertations

Prostaglandin signaling temporally regulates actin cytoskeletal remodeling during Drosophila oogenesis, Andrew James Spracklen
Theses and Dissertations

The role of TIM-1 in enveloped virus entry, Sven Henrik Moller-Tank
Theses and Dissertations

A tale of two RLPAs : studies of cell division in Escherichia coli and Pseudomonas aeruginosa, Matthew Allan Jorgenson
Theses and Dissertations

Regulation of T cell responses by the surface receptor Tim-3, Jacob Gorman
Theses and Dissertations

Personalized audio warning alerts in medicine, Todd Alan Papke
Theses and Dissertations

Urban Land Use Decouples Plant-Herbivore-Parasitoid Interactions at Multiple Spatial Scales, Amanda E. Nelson, Andrew A. Forbes
Department of Biology Publications

Background Selection as Baseline for Nucleotide Variation across the Drosophila Genome, Josep M. Comeron
Department of Biology Publications

Characterization of miR-888 expression and regulation in endometrial cancer, Adriann Marie Hovey
Theses and Dissertations

Use of zebrafish to test candidate genes and mutations associated with structural birth defects, primarily in cleft lip and palate, Tiffany Lynn Smith
Theses and Dissertations

Hippocampal contributions to language: an examination of referential processing and narrative in amnesia, Jake Christopher Kurczek
Theses and Dissertations

Neutrophil priming and host inflammation: The roles of NOX2 and toll-like receptors, Laura Christine Whitmore
Theses and Dissertations

T cell responses to S-glutathionylated And heteroclitic viral epitopes and CCl2-mediated immune dysregulation in mice infected with a neurotropic coronavirus, Jonathan Anthony Trujillo
Theses and Dissertations

Mechanisms of TLR signaling and cooperation in B lymphocytes, Claire Marie Buchta
Theses and Dissertations

Biochemical characterization of Ebola virus GP, Nicholas Joseph Lennemann
Theses and Dissertations

Why do spiral ganglion neurons die after deafening?, Erin M. Bailey
Theses and Dissertations

Outrunning cancer: marathons, money, and morality, Elisabeth Anne Erickson
Theses and Dissertations

Oncomorphic Tp53 mutations in advanced serous ovarian carcinomas, Pavla Brachova
Theses and Dissertations

Regulation of the Prickle1 and Prickle2 genes and their role in autism spectrum disorders, Lily Paemka
Theses and Dissertations

Effects of CGRP and light in mice: implications for photophobia and migraine, Eric Alan Kaiser
Theses and Dissertations

The induction and regulation of CD4 T cells following respiratory syncytial virus infection, Kayla Ann Weiss
Theses and Dissertations

Regulatory crosstalk and interference between the PCB 126 stimulated AHR and hypoxia stimulated HIF-1α signaling pathways, Sabine Ulrike Vorrink
Theses and Dissertations

Regulation of dynamin-related protein 1-mediated mitochondrial fission by reversible phosphorylation and its contribution to neuronal survival following injury, Andrew Michael Slupe
Theses and Dissertations

Regulator of G protein signaling 6 (RGS6), a multifarious and pleiotropic modulator of G protein coupled receptor signaling in brain, Adele Marie Stewart
Theses and Dissertations

The regulation of CD8 T cell responses by inflammatory cytokines and FcγRIIB, Gabriel Starbeck-Miller
Theses and Dissertations

Sodium salicylate prevents inflammation-associated decreases in phosphorylated-Enos SER1177 in human aortic endothelial cells through an AMPK-dependent mechanism, Kyle John Siefers
Theses and Dissertations

Deafness in the genomics era, Aiden Eliot Shearer
Theses and Dissertations

Genomic copy number variation in schizophrenia, Danielle Song Rudd
Theses and Dissertations

RNA interference therapy for the Spinocerebellar ataxias, Pavitra Shyam Ramachandran
Theses and Dissertations

Mechanisms by which chronic ethanol consumption impairs cutaneous immunity, Corey Patrick Parlet
Theses and Dissertations

The role of cyclic di-GMP in regulating type 3 fimbriae : a colonization factor of Klebsiella pneumonia, Caitlin Nolan Murphy
Theses and Dissertations

Transcription factor activator protein 2C and downstream redox biology effectors in development and carcinogenesis, Anthony Roger Cyr
Theses and Dissertations

Characterizing the role of primary cilia in neural progenitor cell development and neonatal hydrocephalus, Calvin Stanley Carter
Theses and Dissertations

A computational approach for comparative oncogenomics using mouse models, Benjamin Thomas Brett
Theses and Dissertations

The influence of gene polymorphisms, modifiable lifestyle factors, and toxicants on the protective effects of the paraoxonase genes, Laura Elise Badtke
Theses and Dissertations

Wnt/planar cell polarity mechanisms in epilepsy and interactions with ciliopathy, Xue Mei
Theses and Dissertations

Identification and validation of small molecule inhibitors for the Tiam1/SDC1 interaction, Josue Alan Lopez
Theses and Dissertations

Fibrosis development requires mitochondrial Cu,Zn-superoxide dismutase-mediated macrophage polarization, Chao He
Theses and Dissertations

Toxicological and therapeutic implications of interactions between polychlorinated biphenyl sulfates and human transthyretin, Fabian Alexander Grimm
Theses and Dissertations

Starting hand position effects on arm configuration for targeted reaching movements, Steven Ewart
Theses and Dissertations

Regulation of virulence gene expression by Rsm homologs in Pseudomonas aeruginosa, Manisha Regina Diaz
Theses and Dissertations

Targeted Deletion of Sox10 by Wnt1-cre Defects Neuronal Migration and Projection in the Mouse Inner Ear, YanYan Mao, Simone Reiprich, Michael Wegner, Bernd Fritzsch
Department of Biology Publications

Effects of transcranial direct current stimulation in combination with motor practice on dexterous grasping and manipulation in healthy older adults, Pranav J. Parikh, Kelly J. Cole
Department of Health and Human Physiology Publications

Sequential adaptive introgression of the mitochondrial genome in Drosophila yakuba and Drosophila santomea, Ana Llopart, Danielle Herrig, Evgeny Brud, Zachary Stecklein
Department of Biology Publications

Examining mechanisms of virulence gene regulation and the early host interactions in Francisella tularenisis, Matthew Leon Faron
Theses and Dissertations

Mutagenesis and structural analysis of the Staphylococcus Aureus Sae two-component system reveals the intricate nature of virulence regulation, Caralyn E. Flack
Theses and Dissertations

Fate of Francisella tularensis capsule and O-antigen mutants in human macrophages, Alicia Janelle Zimbeck
Theses and Dissertations

Regulation of protein trafficking by Ral GTPases and Exocyst in epithelial cells, Yu-Tsan Liu
Theses and Dissertations

Chemosensory regulation of development and heme homeostasis in Myxococcus xanthus, Cynthia Lynn Darnell
Theses and Dissertations

Identification of nuclear receptors that regulate renin gene expression, Ko-Ting Lu
Theses and Dissertations

The role of neuronal mTORC1 signaling in the regulation of physiological processes, Kenjiro Muta
Theses and Dissertations

Identification and characterization of CEP131 as a novel BBSome interacting protein, Xitiz Chamling
Theses and Dissertations

Manipulation of the innate immune response and evasion of macrophage host defense mechanisms by Francisella tularensis, Matthew Eugene Long
Theses and Dissertations

Mechanisms for activation and inhibition of inflammasomes, John Roger Janczy
Theses and Dissertations

Tentative Identification of Hydroxylated 2,2',3,5',6-pentachlorobiphenyl Metabolites in Whole Poplar Plants by a Combination of Chromatographic and Spectrometry Techniques, Cunxian Ma
Theses and Dissertations

Human semen contains exosomes with potent anti-HIV-1 activity, Marisa N. Madison, Richard J. Roller, Chioma M. Okeoma
Department of Microbiology Publications

With Whom Do We Speak? Building Transdisciplinary Collaborations in Rhetoric of Science, Caroline Gottschalk Druschke
Poroi

Applying human computation methods to information science, Christopher Glenn Harris
Theses and Dissertations

Microrna regulation of central nervous system development and their species-specific role in evolution, Hayley Sarah McLoughlin
Theses and Dissertations

Novel roles for y-Protocadherins in the choroid plexus, Mark Albert Lobas
Theses and Dissertations

Manganoporphyrins as adjuvants to enhance pharmacological ascorbate in pancreatic cancer therapy, Malvika Rawal
Theses and Dissertations

A forward genetics approach to identify molecular drivers of liver cancer using Sleeping Beauty mouse models, Jesse Daniel Riordan
Theses and Dissertations

Regulation of CGRP gene expression and effects on light aversive behavior, Ann Christine Raddant
Theses and Dissertations

Characterization of Cis-acting partners within the cytomegalovirus major immediate-early enhancer that strengthen MIE gene expression and viral fitness, Courtney Searcey Galle
Theses and Dissertations

Elucidating mechanisms by which substance P in the RVM contributes to the maintenance of pain following inflammatory injury, Uche Patrick Maduka
Theses and Dissertations

The roles of N-Myc and L-Myc during inner ear neurosensory development, Benjamin Joseph Kopecky
Theses and Dissertations

Genetic determinants of Metabolic Syndrome in Lyon Hypertensive rats, Man Chun John Ma
Theses and Dissertations

Endothelial agonists stimulate VWF release in vitro and trigger TTP in vivo, Gilbert Van Schaeffer
Theses and Dissertations

The molecular mechanisms of PITX2 in tooth development and enamel defects in Axenfeld-Rieger Syndrome, Xiao Li
Theses and Dissertations

Defining the interaction of ESXA and LCRF with Type III secretion system gene promoters, Jessica Marie King
Theses and Dissertations

Population pharmacokinetics and exposure toxicity analysis of Vatalanib in patients with myelodysplastic syndromes, Xiaofeng Wang
Theses and Dissertations

Ear manipulations help model neuroplasticity limitations, Karen Louise Elliott Thompson
Theses and Dissertations

The related kinases FAK and Pyk2 serve distinct functions in TCR-mediated T cell activation, Nicole Chapman
Theses and Dissertations

Biosphere-human feedbacks: a physical geography perspective, George P. Malanson
George P Malanson

Introgression in the Drosophila subobscura - D. Madeirensis sister species: evidence of gene flow in nuclear genes despite mitochondrial differentiation, Danielle K. Herrig, Alec J. Modrick, Evgeny Brud, Ana Llopart
Department of Biology Publications

The Drosophila auditory system, Grace Boekhoff-Falk, Daniel F. Eberl
Department of Biology Publications

Physiological, anatomical, and behavioral changes after acoustic trauma in Drosophila melanogaster, K. W. Christie, E. Sivan-Loukianova, W. C. Smith, B. T. Aldrich, M. A. Schon, M. Roy, B. C. Lear, D. F. Eberl
Department of Biology Publications

Production of and Response to the Cannibalism Peptide SDP in Bacillus subtilis, Tiara G. Perez Morales
Theses and Dissertations

Dual Role of Oxidative Stress in Head and Neck Cancer Chemotherapy: Cytotoxicity and Pro-survival Autophagy, Arya Sobhakumari
Theses and Dissertations

The Mechanisms and Consequences of Gene Suppression During the Unfolded Protein Response, Angela Marie Arensdorf
Theses and Dissertations

Elucidating a Role for CEP290 in Bardet-Biedl Syndrome and other Cilia-related Disorders, Yan Zhang
Theses and Dissertations

Size-Weight Scaling in Healthy Young and Old Adults, Alyssa Lynn Capper
Theses and Dissertations

Regulation and function of Staphylococcus aureus secreted proteases on biofilm integrity, Joe Michael Mootz
Theses and Dissertations

Characterization of a Cdc42 effector protein (Cep4l) and a novel role for Cdc42 in xenopus neurogenesis and Fgf signaling, Alissa Marie Hulstrand
Theses and Dissertations

Studies of Proliferating Cell Nuclear Antigen Mutant Proteins Defective in Translesion Synthesis and Mismatch Repair, Lynne Margaret Dieckman
Theses and Dissertations

Function and Activation Mechanism of PLEKHG2, A Novel G Beta Gamma-Activated RhoGEF in Leukemia Cells, Caitlin M. Runne
Theses and Dissertations

The effects of preeclampsia on signaling to hematopoietic progenitor cells, Donna Santillan, Wendy Hamilton, Ashley Christensen, Katelyn Talcott, Lindsay Gravatt, Mark Santillan, Stephen Hunter
Mark K. Santillan

University of Iowa Dept. of Obstetrics and Gynecology partners with Preeclampsia Foundation, Mark K. Santillan
Mark K. Santillan

Preeclampsia and MicroRNAs, Eric Devor, Donna Santillan, Mark Santillan
Mark K. Santillan

Preeclampsia and MicroRNAs, Eric Devor, Donna Santillan, Mark Santillan
Donna A. Santillan

The effects of preeclampsia on signaling to hematopoietic progenitor cells, Donna Santillan, Wendy Hamilton, Ashley Christensen, Katelyn Talcott, Lindsay Gravatt, Mark Santillan, Stephen Hunter
Donna A. Santillan

Distribution, elimination and toxicity assessment of semi-volatile polychlorobiphenyls after inhalation exposure, Xin Hu
Theses and Dissertations

The role of mitochondrial restructuring in neuronal calcium homeostasis and excitotoxicity, Patrick Ryan Houlihan
Theses and Dissertations

Focal adhesion kinase signaling regulates highly productive transduction of adeno-associated virus through integrin-mediated endocytosis, Paul Michael Kaminsky
Theses and Dissertations

GB virus C interactions with HIV: effects on immunoactivation and mechanisms of immunomodulation, Nirjal Bhattarai
Theses and Dissertations

Mechanisms Of MicroRNA evolution, regulation and function: computational insight, biological evaluation and practical application, Ryan Michael Spengler
Theses and Dissertations

Loss of acid sensing ion channel-1a and bicarbonate administration attenuate the severity of traumatic brain injury, Terry Yin
Theses and Dissertations

Investigating the genetics Of thyroid stimulating hormone in newborns, Farah Yacoub Alul
Theses and Dissertations

More than milk and cookies: a cultural analysis of the college play day, Sarah Jane Eikleberry
Theses and Dissertations

Characterization of calcium binding protein 1 (CaBP1/CD) expression and localization in the mouse brain, Kristin Kim
Theses and Dissertations

Gene therapies for spinocerebellar ataxia type 1, Megan Kathryn Keiser
Theses and Dissertations

Beyond relational: a database architecture and federated query optimization in a multi-modal healthcare environment, Ray Hales Hylock
Theses and Dissertations

Effects of moderate to vigorous-intensity physical activity on nocturnal and next day hypoglycemia in adolescents with Type 1 Diabetes, Kristen Marie Metcalf
Theses and Dissertations

Modulation of TRPV1, nociceptor sensitization , and induction of thermal hyperalgesia by C-type natriuretic peptide, Lipin Loo
Theses and Dissertations

"Minimum essential adjustments": gender, physicality, and equality at the United States Military Academy, 1976-1980, Amanda Kay Curtis
Theses and Dissertations

Characterization of the neutrophil respiratory burst during infection with Francisella novicida, Drew Clair Fayram
Theses and Dissertations

Catalase attenuates pulmonary fibrosis while increasing pro-inflammatory cytokines, Lei Shi
Theses and Dissertations

A matter of life or death: modulation of neutrophil apoptosis and complement activation by Francisella tularensis, Justin Todd Schwartz
Theses and Dissertations

Knowledge transfer: what, how, and why, Si-Chi Chin
Theses and Dissertations

A saga of power, money, and sex in women's athletics: a presidents' history of the Association for Intercollegiate Athletics for Women (AIAW), Amy Sue Wilson
Theses and Dissertations

Preeclampsia and MicroRNAs, Eric Devor, Donna Santillan, Mark Santillan
Eric J Devor

The effects of preeclampsia on signaling to hematopoietic progenitor cells, Donna Santillan, Wendy Hamilton, Ashley Christensen, Katelyn Talcott, Lindsay Gravatt, Mark Santillan, Stephen Hunter
Stephen K. Hunter

Identification of Rtl1, a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis, Jesse D. Riordan, Vincent W. Keng, Barbara R. Tschida, Todd E. Scheetz, Jason B. Bell, Kelly M. Podetz-Pedersen, Catherine D. Moser, Neal G. Copeland, Nancy A. Jenkins, Lewis R. Roberts, David A. Largaespada, Adam J. Dupuy
Department of Anatomy and Cell Biology Publications

Mark K. Santillan, MD, Kristina W. Thiel
Proceedings in Obstetrics and Gynecology

The effects of preeclampsia on signaling to hematopoietic progenitor cells, Donna A. Santillan, Wendy S. Hamilton, Ashley Christensen, Katelyn M. Talcott, Lindsay K. Gravatt, Mark K. Santillan, Stephen K. Hunter
Proceedings in Obstetrics and Gynecology

Preeclampsia and MicroRNAs, Eric J. Devor, Donna A. Santillan, Mark K. Santillan
Proceedings in Obstetrics and Gynecology

University of Iowa Dept. of Obstetrics and Gynecology partners with Preeclampsia Foundation, Mark K. Santillan
Proceedings in Obstetrics and Gynecology

Natural killer cell activation, trafficking, and contribution to immune responses to viral pathogens, Lindsey Elizabeth Carlin
Theses and Dissertations

FHIT inactivation combined with cigarette smoke enhances the oxidative stress response, Jennifer A. Boylston
Theses and Dissertations

Understanding the contribution of individual zinc fingers to a multi-functional, polydactyl transcription factor, Ryan M. Baxley
Theses and Dissertations

SEPP1 and FoxM1 regulate oxidative stress-mediated radiation response, Jaimee Claire Eckers
Theses and Dissertations

Pharmacological dissection of the actions of the Mu opioid receptor in the Rostroventral medial medulla, Marlene Cano
Theses and Dissertations

The role of MnSOD and sirtuin 3 in thymocyte responses to radiation and lymphomagenesis, Gaowei Mao
Theses and Dissertations

The two-component system, ArlRS, regulates agglutination and pathogenesis in Staphylococcus aureus, Jennifer Nicole Walker
Theses and Dissertations

Molecular basis of Nod1 And Nod2 signaling, Aaron Martin Ver Heul
Theses and Dissertations

Effects of three deafness-causing gamma-actin mutations on actin structure and function, Karina Annette Kruth
Theses and Dissertations

Generation and characteriztion of regulatory dendritic cells for the amelioration of acute graft versus host disease, Sabrina Marie Scroggins
Theses and Dissertations

Priming and tracking the virus-specific T cell response, Daniel Scott McDermott
Theses and Dissertations

Utilizing high-throughput genomics methodologies to explore transcritomes and exomes, Xiaojing Hong
Theses and Dissertations

A novel role for prolyl-hydroxylase 3 gene silencing in epithelial-to-mesenchymal-like transition, Trenton Lane Place
Theses and Dissertations

Dystroglycan in cerebellar development and disease, Huy Tuan Nguyen
Theses and Dissertations

Taking shape : regulating mitochondria morphology through alternative splicing and phosphorylation of fission factor proteins, Theodore James Wilson
Theses and Dissertations

Discoveries on the storage of red blood cells and the exposure of cells in culture to xenobiotics, Thomas Joost van 't Erve
Theses and Dissertations

Secreted virulence factors in lethal illness due to Staphylococcus aureus, Adam Russell Spaulding
Theses and Dissertations

Improving lentiviral vector-mediated gene transfer by understanding cellular barriers, Mayumi Oakland
Theses and Dissertations

The molecular evolution of reproduction in animals: insights from sexual and asexual rotifers, Sara Jeanette Hanson
Theses and Dissertations

Macrophage microRNA and mRNA responses to stimulation of TLRs or upon infection with Leishmania infantum chagasi, Erik Bruce Wendlandt
Theses and Dissertations

The evolution and expression of Drosophila meiosis genes, Danielle Jeanine Beekman
Theses and Dissertations

A prickly situation: Prickle1 function depends on the signaling context, Tian Yang
Theses and Dissertations

Retroviral mutagenesis in a newly developed myc transgenic mouse model of human B cell and plasma cell neoplasia, Samuel Robert Lifton
Theses and Dissertations

The role Of sirtuin3 in regulating mitochondrial superoxide metabolism in response to ionizing radiation in mouse embryonic fibroblasts., Kranti Ashok Mapuskar
Theses and Dissertations

Global analysis of alternative polyadenylation regulation using high-throughput sequencing, Ji Wan
Theses and Dissertations

Cancer gene discovery and immunosurveillance studies using Sleeping Beauty mouse models, Laura Marie Rogers
Theses and Dissertations

Regulation of protein phosphatase 2A by proteasomal degradation, Elizabeth Anne Oberg
Theses and Dissertations

The role of Parf, a novel partner of ARF, in pancreatic ductal adenocarcinoma and in ARF signaling, Viviane Palhares Muniz
Theses and Dissertations