Document Type

Thesis

Date of Degree

Spring 2016

Degree Name

MS (Master of Science)

Degree In

Biomedical Engineering

First Advisor

Hans J. Johnson

Abstract

Rapid development of domain specialized medical imaging tools is essential for deploying medical imaging technologies to advance clinical research and clinical practice. This work describes the development process, deployment method, and evaluation of modules constructed within the 3D Slicer environment. These tools address critical problems encountered in four different clinical domains: quality control review of large repositories of medical images, rule-based automated label map cleaning, quantification of calcification in the heart using low-dose radiation scanning, and waist circumference measurement from abdominal scans. Each of these modules enables and accelerates clinical research by incorporating medical imaging technologies that minimize manual human effort. They are distributed within the multi-platform 3D Slicer Extension Manager environment for use in the computational environment most convenient to the clinician scientist.

Public Abstract

Rapidly creating specialized medical imaging tools is essential for distributing medical imaging tools to advance clinical research and clinical practice. This work describes the development process, deployment method, and evaluation of modules constructed within the free image viewing software called 3D Slicer. These tools address critical problems encountered in four different clinical areas: quality assessment of large numbers of medical images, automatic corrections of three-dimensional computer representations of the brain, quantification of calcification in the heart using low-dose radiation scanning, and waist circumference measurement from abdominal scans. Each of these applications enables and accelerates clinical research by including medical imaging technologies that minimize manual human effort.

Keywords

publicabstract, Agatston Scoring, ImageEval, Label Atlas, Medical Imaging, Slicer, Waist Circumference

Pages

xi, 91

Bibliography

87-91

Copyright

Copyright 2016 Jessica LeeAnn Forbes

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