Document Type

Thesis

Date of Degree

Spring 2016

Degree Name

MS (Master of Science)

Degree In

Biomedical Engineering

First Advisor

Sarah Vigmostad

Abstract

Cardiovascular disease is the number one reason for emergency room visits in the United States. Understanding the different pathologies of the cardiovascular system is crucial when trying to prescribe proper treatment or intervention. In order best understand these issues proper computer simulations would be necessary. Due to the fact that every patient is different. Being able to analysis and properly simulate each patients data individually to better understanding their specific case is necessary for patient specific interventions. In order to achieve such requirement we propose a new method of mesh generation to better map patient specific geometries. This new framework takes a set of points in a 3D space and generates a 2D NURBS mesh. Insuring a smooth and accurate representation of the patient specific geometry will allow for more specific incite to possible medical issues that may arise. This NURBS based mesh can be then used to run either finite element analysis, computational fluid dynamics, or even fluid solid interactions. Running these patient-specific valve simulations using isogementric modeling is what will allow us to have patient specific treatments and intervention.

Public Abstract

Cardiovascular disease is the number one reason for emergency room visits in the United States. Understanding the different pathologies of the cardiovascular system is crucial when trying to prescribe proper treatment or intervention. In order best understand these issues proper computer simulations would be necessary. Due to the fact that every patient is different. Being able to analysis and properly simulate each patients data individually to better understanding their specific case is necessary for patient specific interventions. In order to achieve such requirement we propose a new method of mesh generation to better map patient specific geometries. This new framework takes a set of points in a 3D space and generates a 2D NURBS mesh. Insuring a smooth and accurate representation of the patient specific geometry will allow for more specific incite to possible medical issues that may arise. This NURBS based mesh can be then used to run either finite element analysis, computational fluid dynamics, or even fluid solid interactions. Running these patient-specific valve simulations using isogementric modeling is what will allow us to have patient specific treatments and intervention.

Keywords

publicabstract, Automated, Mesh, Mitral, NURBS, Patient, Valves

Pages

xi, 49

Bibliography

48-49

Copyright

Copyright 2016 Moustafa Ibrahim

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