Poster Title (Current Submission)

Predicting Viscosity in the Synthesis of Controlled-Release Hydrogels

Major(s)

Biochemistry, Chemical & Biochemical Engineering

Minor(s)

Chemistry, Mathematics, Spanish

Mentor Name

Dr. Eric Nuxoll

Mentor Department

Chemical and Biochemical Engineering

Presentation Date

March 2011

Abstract

In order to create composite polymer films containing suspended particles, the reaction mixture cannot be poured into sheets until its viscosity has risen substantially. Exponential viscosity change over time, however, makes consistent pouring difficult. Reaching the target viscosity varies widely with time, forcing continuous monitoring of the reaction mixture. Mixture viscosity was correlated with visual observations, and viscosity versus time profiles modeled reaction conditions, revealing the key variable for onset of rapid viscosity change to be rate of temperature change in the mixture. Estimates of appropriate heating time can now commence shortly after starting the reaction, and be refined throughout the process.

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Mar 26th, 12:00 AM

Predicting Viscosity in the Synthesis of Controlled-Release Hydrogels

In order to create composite polymer films containing suspended particles, the reaction mixture cannot be poured into sheets until its viscosity has risen substantially. Exponential viscosity change over time, however, makes consistent pouring difficult. Reaching the target viscosity varies widely with time, forcing continuous monitoring of the reaction mixture. Mixture viscosity was correlated with visual observations, and viscosity versus time profiles modeled reaction conditions, revealing the key variable for onset of rapid viscosity change to be rate of temperature change in the mixture. Estimates of appropriate heating time can now commence shortly after starting the reaction, and be refined throughout the process.