Document Type

Article

Peer Reviewed

1

Publication Date

9-19-2014

NLM Title Abbreviation

Transplant Proc

Journal/Book/Conference Title

Transplantation Proceedings

PubMed ID

25242792

DOI of Published Version

10.1016/j.transproceed.2014.06.047

Abstract

BK polyoma viral infection occurs as an asymptomatic infection in a high proportion of normal hosts without obvious sequelae. In the kidney transplant population, the virus is reactivated because of reduced immunity and, if not appropriately managed, can lead to BK viral nephropathy, which has emerged as a common cause of acute kidney injury and progressive chronic kidney disease in renal transplant recipients. BK viremia almost always occurs during the first 2 years after transplantation, when immunosuppressive therapy is high, or at other periods when immunosuppression is intensified. BK viremia is now detected by routine screening of transplant patients for the first few years, and BK viral nephropathy is considered to be high in the differential diagnosis of acute kidney injury in recently transplanted patients. We report a case of BK viral nephropathy developing 10 years after transplantation and present the challenges of managing advanced disease.

Keywords

OAfund

Journal Article Version

Version of Record

Published Article/Book Citation

Transplantation Proceedings 46:7 (2014) pp. 2386-2390, doi:10.1016/j.transproceed.2014.06.047

Rights

Copyright © 2014, J.C. Mathew, D.G. Holanda, T.L. Figanbaum, M. Fraer, C.P. Thomas. Posted by permission.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Share

COinS
 

URL

https://ir.uiowa.edu/internalmedicine_pubs/6