Title

Depot medroxyprogesterone acetate and bone mineral density in adolescents - The black box warning: A position paper of the society for adolescent medicine

Document Type

Article

Peer Reviewed

1

Publication Date

1-1-2006

Journal, Book or Conference Title

Journal of Adolescent Health

NLM Title Abbreviation

J Adolesc Health

PubMed ID

16857545

DOI

10.1016/j.jadohealth.2006.03.011

Abstract

The purpose of this Position Paper is to review the published Black Box Warning regarding depot medroxyprogesterone acetate (DMPA) and bone loss as it relates to adolescent girls. The scientific findings that prompted the Food and Drug Administration to issue the warning are reviewed and the following additional issues are considered: (1) likely low risk of fracture related to DMPA use, (2) evidence of at least partial recovery after discontinuation of the method, and (3) the need to balance the physical, social and economic cost of adolescent pregnancy versus the immediate and long-term impact of DMPA on bone. A list of clinical guidelines is included, the main recommendation of which is to continue prescription of DMPA, with counseling about the risks and benefits, in most of the adolescent population desiring to use this contraceptive method. (c) 2006 Society for Adolescent Medicine. All rights reserved.

Published Article/Book Citation

The definitive version was published in Journal of Adolescent Health, 39:2 (2006) pp.296-301. DOI:10.1016/j.jadohealth.2006.03.011.

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URL

http://ir.uiowa.edu/nursing_pubs/178