Title

Perceived stress in prodromal Huntington disease

Document Type

Article

Peer Reviewed

1

Publication Date

1-1-2012

Journal/Book/Conference Title

Psychology & Health

Volume

27

NLM Title Abbreviation

Psychol Health

DOI

10.1080/08870446.2010.529141

PubMed ID

21623544

Abstract

This study examines perceived stress and its relationship to depressive symptoms, life changes and functional capacity in a large sample of individuals who are positive for the Huntington disease (HD) gene expansion but not yet diagnosed. Participants were classified by estimated proximity to HD diagnosis (far, mid, near) and compared with a non-gene-expanded comparison group. Persons in the mid group had the highest stress scores. A significant interaction between age and time since HD genetic testing was also found. Secondary analyses using data from a different data collection point and including a diagnosed group showed the highest stress scores in the diagnosed group. Possible explanations and implications are discussed.

Keywords

Adult, Depression, Female, Genetic Predisposition to Disease/psychology, Humans, Huntington Disease/genetics/psychology, Longitudinal Studies, Male, Middle Aged, Self Report, Stress, Psychological/epidemiology/psychology, Young Adult



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URL

http://ir.uiowa.edu/nursing_pubs/1827