Patents assigned to the University of Iowa, by faculty and researchers at the University of Iowa.

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Submissions from 2018

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US Patent 9,856,204 Methods for inhibiting muscle atrophy, Christopher M. Adams, Steven D. Kunkel, Manish Suneja, and Michael Welsh

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US Patent 9,891,301 Apparatus and methods for dynamical tracking of mechanical activity within cell populations, Barry London, Vladimir Shusterman, and Xiaodong Zhu

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US Patent 9,861,802 Catheters, catheter systems, and methods for puncturing through a tissue structure, Steven Richard Mickelsen

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US Patent 9,884,052 Compounds and methods to treat organophosphorus poisoning, Daniel M. Quinn and Joseph John Topczewski

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US Patent 9,865,660 Organic magnetoelectroluminescence for transduction between magnetic and optical information, Markus Wohlgenannt, Michael Flatte, Andrew Kent, Fujian Wang, Nicholas Harmon, and Ferran Macia Bros

Submissions from 2017

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US Patent 9,545,196 Automated assessment of glaucoma loss from optical coherence tomography, Michael Abramoff and Milan Sonka

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US Patent 9,539,367 Gallium inhibits biofilm formation, Bradley E. Britigan and Pradeep K. Singh

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US Patent 9,849,195 Methods and compositions for treating brain diseases, Beverly L. Davidson

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US Patent 9,650,631 Reduction of off-target RNA interference toxicity, Beverly L. Davidson, Alejandro Mas Monteys, Jodi L. Mcbride, and Ryan Boudreau

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US Patent 9,540,659 Modified adeno-associated virus vector compositions, Beverly L. Davidson, Maria Scheel, Ryan Boudreau, and Alejandro Mas Monteys

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US Patent 9,806,710 Voltage-controlled magnetic-based devices having topological insulator/magnetic insulator heterostructure, Michael Flatté

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US Patent 9,776,017 Method and system for dynamically-trimmed spot scanning for ion therapy, Ryan Flynn, Daniel Hyer, Dongxu Wang, Patrick Hill, and Yves Claereboudt

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US Patent 9,624,497 Nucleic acid aptamers, Paloma Giangrande, Francis Miller, and William Thiel

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US Patent 9,572,976 System that secures an electrode array to the spinal cord for treating back pain, Matthew A. Howard, Hiroyuki Oya, Steve Viljoen, and Chandan G. Reddy

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US Patent 9,595,171 Methods and systems for augmentative and alternative communication, Richard Hurtig, Benjamin Berkowitz, Blake Earl Martinson, Zihan Zhu, and Richard Rives Bird

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US Patent 9,730,988 Parasitic biological agents for treatment and prevention of graft versus host disease, Mirac Nedim Ince, David E. Elliott, and George J. Weiner

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US Patent 9,669,115 Co-crystals and salts of contrast agents and imaging, Leonard R. Macgillivray

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US Patent 9,603,949 Oligonucleotide-based probes for detection of bacterial nucleases, James O. Mcnamara II, Katie R. Stockdale, Lingyan Huang, Alexander R. Horswill, Mark A. Behlke, and Frank J. Hernandez

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US Patent 9,724,170 Catheters, catheter systems, and methods for puncturing through a tissue structure and ablating a tissue region, Steven Richard Mickelsen

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US Patent 9,572,894 Biodegradable particulate formulations, Aliasger K. Salem, Sean M. Geary, George J. Weiner, Caitlin Lemke, and Yogita Krishnamachari

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US Patent 9,758,781 Methods to prevent and treat autosomal dominant non-syndromic hearing loss, Richard J. H. Smith and Seiji Shibata

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US Patent 9,649,357 Treatment of chronic nephropathies using soluble complement receptor type I (sCR1), Richard J. H. Smith, Yuzhou Zhang, and Henry C. Marsh

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US Patent 9,801,922 Compositions and methods of treating cancer, Douglas R. Spitz, Michael K. Schultz, Kyle Kloepping, Yueming Zhu, Nukhet Aykin-burns, and Max S. Wicha

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US Patent 9,611,301 GB virus C (hepatitis G virus) E2 glycoprotein as an immunomodulatory agent, Jack T. Stapleton, Nirjal Bhattarai, Jinhua Xiang, and James H. Mclinden

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US Patent 9,750,516 Positioning device for ankle joint replacement surgery, Yuki Tochigi, Thomas E. Baer, and Charles L. Saltzman

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US Patent 9,820,651 Methods and devices for labeling and/or matching, Juerg Tschirren, Milan Sonka, Joseph Reinhardt, Geoffrey Mclennan, and Eric Hoffman

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US Patent 9,661,831 Transgenic pig models of cystic fibrosis, Michael J. Welsh and David A. Stoltz

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US Patent 9,745,331 Therapeutic bisphosphonates, David Wiemer

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US Patent 9,828,587 Chimeric adeno-associated virus/ bocavirus parvovirus vector, Ziying Yan, John F. Engelhardt, and Jianming Qiu

Submissions from 2016

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US Patent 9,254,295 Tomatidine, analogs thereof, compositions comprising same, and uses for same, Christopher M. Adams, Michael C. Dyle, and Michael Welsh

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US Patent 9,295,664 Methods for lowering blood glucose, Christopher M. Adams, Steven D. Kunkel, and Michael Welsh

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US Patent 9,422,248 Phenyl- and pyridinyl-substituted 2,2,2-trifluoroethanols having anticonvulsant properties, Max T. Baker and Rajesh K. Mishra

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US Patent 9,345,776 Biodegradable polymers with sulfenamide bonds for drug delivery applications, Ned B. Bowden, Denison J. Kuruvilla, Aliasger K. Salem, and Jun Yoo

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US Patent 9,387,210 Inhibitors of phosphodiesterase type 5A for treating or preventing muscle disease or the symptoms thereof in a patient, Kevin P. Campbell, Yvonne M. Kobayashi, and Robert W. Crawford

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US Patent 9,238,040 Chemoprevention of colorectal cancer by mesalamine/sulfasalazine, Kiron M. Das and Jim Jung-ching Lin

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US Patent 9,523,093 Huntington's disease therapeutic compounds, Beverly L. Davidson and Alejandro Mas Monteys

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US Patent 9,487,779 siRNA-mediated gene silencing, Beverly L. Davidson, Henry Paulson, Victor Miller, and Cynthia Gouvion

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US Patent 9,260,716 RNA interference suppression of neurodegenerative diseases and methods of use thereof, Beverly L. Davidson, Haibin Xia, Qinwen Mao, Henry Paulson, Ryan Boudreau, and Scott Harper

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US Patent 9,388,410 Alternative export pathways for vector expressed RNA interference, Scott Harper and Beverly L. Davidson

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US Patent 9,435,721 Isolation and characterization of tumor cells using shear stress measurements, Michael D. Henry and Matthew J. Barnes

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US Patent 9,416,149 Methods to modulate Rac1 import and to treat pulmonary fibrosis, Raymond J. Hohl and Brent A. Carter

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US Patent 9,403,008 Managing back pain by applying a high frequency electrical stimulus directly to the spinal cord, Matthew A. Howard

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US Patent 9,254,379 System that secures an electrode array to the spinal cord for treating back pain, Matthew A. Howard, Hiroyuki Oya, Steve Viljoen, and Chandan G. Reddy

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US Patent 9,364,660 Electrode array device configured for placement inside the dura for direct spinal cord stimulation, Matthew Howard, Timothy Brennan, Brian Dalm, Marcel Utz, George T. Gillies, Steven Scott, Randall S. Nelson, and Robert Shurig

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US Patent 9,486,621 Implanting an electrode array against the spinal cord inside the dura for stimulating the spinal cord and treating pain, Matthew Howard, Timothy Brennan, Brian Dalm, Marcel Utz, George T. Gillies, Steven Scott, Randall S. Nelson, and Robert Shurig

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US Patent 9,346,781 Therapeutic compounds, Zhendong Jin and Lei Chen

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US Patent 9,428,493 Schweinfurthin analogues, John Kodet, Jeffrey D. Neighbors, and David F. Wiemer

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US Patent 9,370,529 Tannin inhibitors of HIV, George A. Kraus and Wendy Maury

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US Patent 9,506,085 Ammonia production using bioelectrocatalytical devices, Johna Leddy and Timothy Michael Paschkewitz

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US Patent 9,272,016 Methods to enhance RNAi oligonucleotide delivery to respiratory epithelial cells, Paul B. Mccray Jr., Beverly L. Davidson, and Sateesh Krishnamurthy

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US Patent 9,506,843 Personal nanoparticle respiratory depositions sampler and methods of using the same, Thomas Peters and Lorenzo Cena

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US Patent 9,428,494 Therapeutic compounds, Thomas Prisinzano

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US Patent 9,249,100 Compounds and methods to treat organophosphorus poisoning, Daniel M. Quinn and Joseph John Topczewski

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US Patent 9,295,713 Treatment of chronic nephropathies using soluble complement receptor type I (sCR1), Richard J. H. Smith, Yuzhou Zhang, and Henry C. Marsh

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US Patent 9,274,429 Method for producing layered materials using long-lived photo-induced active centers, Cynthia G. Templeman, Alec B. Scranton, Beth Ann Rundlett, and Cynthia Hoppe

Submissions from 2015

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US Patent 9,063,139 Variants in complement regulatory genes predict age-related macular degeneration, Rando L. Allikmets, Gregory S. Hageman, Michael C. Dean, and Albert M. Gold

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US Patent 9,168,307 Mitochondrial-targeted cationic nanoparticles comprising CaMKII inhibitors and uses thereof for treating and preventing diseases and disorders associated with CaMKII activity, Mark E. Anderson, Mei-ling A. Joiner, Aliasger K. Salem, Amaraporn Wongrakpanich, Frederick E. Domann, Duane D. Hall, Olha M. Koval, and Douglas R. Spitz

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US Patent 9,090,701 Methods of detecting oxidized calcium/calmodulin dependent protein kinase II, Mark E. Anderson, Peter J. Mohler, Douglas R. Spitz Jr., and Jeffrey Robert Erickson

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US Patent 8,981,012 Modified polydicyclopentadienes, Ned B. Bowden and Mathew Perring

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US Patent 9,193,777 Method of treating cardiac arrhythmia with long acting atrial natriuretic peptide(LA-ANP), John C. Burnett Jr., Timothy M. Olson, Leonid V. Zingman, and Denice Marie Hodgson-zingman

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US Patent 9,181,544 Therapeutic compounds, Beverly L. Davidson and Ryan L. Boudreau

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US Patent 9,169,483 RNA interference suppression of neurodegenerative diseases and methods of use thereof, Beverly L. Davidson, Alejandro Mas Monteys, and Ryan L. Boudreau

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US Patent 9,125,967 Fluorapatite glass-ceramics, Isabelle Denry and Julie Holloway

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US Patent 9,119,957 Cochlear implant system component having multiple electrode assemblies, Bruce J. Gantz, James Finlay Patrick, and John L. Parker

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US Patent 9,163,242 HER2 nucleic acid aptamers, Paloma H. Giangrande, James O. Mcnamara, Kristina W. Thiel, William Thiel, and William M. Rockey

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US Patent 9,139,835 Nucleic acid aptamers, Paloma Giangrande, Francis Miller, and William Thiel

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US Patent 9,063,118 Isolation and characterization of tumor cells using shear stress measurements, Michael D. Henry and Matthew J. Barnes

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US Patent 9,056,005 Methods and devices for arytenoid repositioning, Henry T. Hoffman

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US Patent 9,181,291 Tannin inhibitors of HIV, George A. Kraus and Wendy Maury

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US Patent 9,050,264 Cellulose capsules and methods for making them, Vijay Kumar and Bhavik Bhatt

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US Patent 8,951,498 Synthesis of hierarchical nanocrystalline zeolites with controlled particle size and mesoporosity, Sarah Larsen and Anton Petushkov

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US Patent 8,940,510 Spray dried microbes and methods of preparation and use, Venkiteswaran Subramanian, James H. Glenn IV, and Shuvendu Das

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US Patent 8,951,752 N-demethyase genes and uses thereof, Venkiteswaran Subramanian, Michael Tai-man Louie, and Ryan Summers

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US Patent 8,993,042 Method for determining the production parameters for a substrate coating process, Cynthia Gazepis Templeman, Alec B. Scranton, Beth Ann Ficek, and Cynthia Hoppe

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US Patent 9,211,347 Method of delivering vectors to pancreas and lungs by cannulating the aorta, Aliye Uc, Paul B. Mccray, Beverly L. Davidson, and Abhay Divekar

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US Patent 9,192,633 Use of parasitic biological agents for disease prevention and control, Joel V. Weinstock and David E. Elliott

Submissions from 2014

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US Patent 8,794,230 Articulated oral airway, Ron Owen Abrons

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US Patent 8,841,423 Monoclonal antibodies specific for oxidized calcium/calmodulin dependent protein kinase II, Mark E. Anderson, Peter J. Mohler, Douglas R. Spitz Jr., and Jeffrey Robert Erickson

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US Patent 8,778,186 High-density polydicyclopentadiene, Ned B. Bowden, Abhinaba Gupta, and Tyler R. Long

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US Patent 8,921,447 Photo-enforced stratification of polymeric materials, Clinton J. Cook and Allan C. Guymon

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US Patent 8,691,948 Methods and compositions for treating brain diseases, Beverly L. Davidson and Yong Hong Chen

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US Patent 8,779,116 SiRNA-mediated gene silencing, Beverly L. Davidson, Henry Paulson, Victor Miller, and Cynthia Gouvion

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US Patent 8,846,030 Compounds and methods to enhance rAAV transduction, John F. Engelhardt and Dongsheng Duan

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US Patent 8,630,721 Hybrid cochlear implant, Bruce J. Gantz

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US Patent 8,685,937 Nucleic acid aptamers, Paloma H. Giangrande, James O. Mcnamara, and Anton P. Mccaffrey

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US Patent 8,691,567 Alternative export pathways for vector expressed RNA interference, Scott Harper and Beverly L. Davidson

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US Patent 8,834,900 Combination motif immune stimulatory oligonucleotides with improved activity, Arthur M. Krieg and Jorg Vollmer

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US Patent 8,846,578 Zinc finger nuclease for the CFTR gene and methods of use thereof, Paul Mccray, Morgan Maeder, and Jae Keith Joung

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US Patent 8,703,469 Baculoviruses with enhanced virion production and a method for the production of baculoviruses, Paul Mccray, Patrick Sinn, and Gary Blissard

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US Patent 8,621,701 Dental brush assembly and method for making the same, Michael R. Meharry

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US Patent 8,680,641 System and method of planar processing of semiconductors into detector arrays, John P. Prineas, Jonathan T. Olesberg, and Chris Coretsopoulos

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US Patent 8,758,387 Biofeedback training of anal and rectal muscles, Satish Sanku Chander Rao and Muralidhar Nukala Sunil Kumar

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US Patent 8,686,016 Schweinfurthins and uses thereof, Karlyne Reilly, Thomas Turbyville, John A. Beutler, and David Wiemer

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US Patent 8,858,946 Method for inhibiting HIV-1 replication utilizing anti-GBV-C E2 antibodies, Jack T. Stapleton, Jinhua Xiang, Donna Klinzman, and James H. Mclinden

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US Patent 8,636,744 Positioning device for ankle joint replacement surgery, Yuki Tochigi, Thomas E. Baer, and Charles L. Saltzman

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US Patent 8,676,302 Systems and methods for multi-spectral bioluminescence tomography, Ge Wang, Alexander Cong X, Weimin Han, Ming Jiang, Haiou Shen, and Wenxiang Cong

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US Patent 8,912,386 Transgenic pig model of cystic fibrosis, Michael J. Welsh, Christopher S. Rogers, Randall S. Prather, John Engelhardt, and Ziying Yan

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US Patent 8,637,685 Schweinfurthin analogues, David F. Wiemer, Jeffrey D. Neighbors, Raymond J. Hohl, and Craig Kuder

Submissions from 2013

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US Patent 8,616,702 Hybrid laser ophthalmoscope, Michael Abrámoff

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US Patent 8,440,656 Methods of treating pulmonary diseases and disorders by modulating calcium/calmodulin dependent protein kinase II activity, Mark E. Anderson, Isabella M. Grumbach, and Joel N. Kline