US Patent 4,163,063
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
Smooth muscle tissue relaxation is produced in mammals by internal administration of a compound of the formula: ##STR1## wherein R is alkyl having 1 to 6 carbon atoms, the novel compound 2-N-isopropylamino-1,2,3,4-tetrahydro-5,6,-dihydroxy-naphthalene being preferred. Relief of bronchial asthma and relaxation of the uterine smooth muscle are among the therapeutic effects produced.
Cannon, Joseph G. and Long, John P. Aminotetralin adrenergic β-agonists. US Patent 4,163,063 filed January 02, 1976 and issued July 31, 1979. https://ir.uiowa.edu/patents/16