Document Type

Patent

Patent Number

US Patent 6,261,814

Patent agency

United States Patent and Trademark Office

Publication Date

7-17-2001

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/030,462

Date Filed

1998-02-25

Total Pages

22 pages

Abstract

The present invention is directed to a novel, biologically-derived carboxylic acid reductase, also referred to herein as an aryl-aldehyde oxidoreductase, that has been isolated and purified from Nocardia sp. strain NRRL 5646, and to methods of using the carboxylic acid reductase as a biocatalyst for the reduction of carboxylic acids or their derivatives to the corresponding useful product(s). In a preferred embodiment, the invention is directed to biochemically-produced vanillin, and to the methods of its production by the biocatalytic reduction of vanillic acid, or a precursor or derivative thereof, in a reaction comprising the substantially purified, biologically-derived carboxylic acid reductase.

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URL

https://ir.uiowa.edu/patents/282