US Patent 7,888,327
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
Krieg, Arthur M. and Kline, Joel N. Methods of using immunostimulatory nucleic acid molecules to treat allergic conditions. US Patent 7,888,327 filed March 25, 2009 and issued February 15, 2011. https://ir.uiowa.edu/patents/533