Immunoglobulin G (IgG) is the major serum immunoglobulin, accounting for roughly 75% of all immunoglobulin. IgG is the only class of immunoglobulin that crosses the placenta and it serves as the main immunologic barrier between the fetus and external environments. There has not been a clear consensus on what the normal values of IgG are throughout pregnancy. The aim of this study is to measure serum immunoglobulin G in each trimester of the pregnant female to determine a normal IgG profile throughout all trimesters in normal pregnancy.
Immunoglobulin G, pregnancy, first trimester, second trimester, third trimester
Copyright © Jena Abel, Jona Conklin, Stephen K. Hunter, Ryan Empey, Eric M. Tyler, Ashley Christensen, Katelyn M. Talcott, Zuhair K. Ballas, Mark K. Santillan, Donna A. Santillan, 2013.
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Taylor J, Conklin J, Hunter SK, Empey R, Tyler EM, Christensen A, Talcott KM, Ballas ZK, Santillan DA, Santillan MK. Defining normal IgG changes throughout pregnancy. Proc Obstet Gynecol. 2013 Jul 03;3(2):Article 8 [2 p.]. https://doi.org/10.17077/2154-4751.1213. Free full text article.