The American Society of Clinical Oncology recommends that full weight-based doses of chemotherapy be used to treat obese patients with cancer. However, many oncologists limit the dose of chemotherapy based on ideal body weight or a maximum body surface area (BSA) of m2. The objective of our study is to determine how weight-based chemotherapy dosing affects toxicity, treatment delays, and laboratory values in a cohort of obese gynecologic cancer patients at our institution. We hypothesize that full weight-based dosing in obese patients does not increase adverse chemotherapy outcomes.
chemotherapy, obesity, dosage
Copyright © Jean Hansen, Jean-Marie Stephan, Michelle Freesmeier, David P. Bender, Koen De Geest, Anna Button, Michael J. Goodheart, 2013
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Hansen J, Stephan J, Freesmeier M, Bender DP, De Geest K, Button A, Goodheart MJ. The effect of weight-based chemotherapy dosing in a cohort of gynecologic oncology patients. Proc Obstet Gynecol. 2013 Dec 31;3(3):Article 9 [2 p.]. https://doi.org/10.17077/2154-4751.1235. Free full text article.