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Objective: Angiosarcoma is a rare neoplasm typically presenting in the skin and superficial soft tissues, with an equal female-to-male ratio. We present a woman with recurrent vulvar lesions and a history of melanoma found to have angiosarcoma.

Case: A 67-year-old woman presented with a seven month history of recurrent vulvar lesions with symptoms of discomfort and bleeding. The histopathological diagnosis revealed high-grade angiosarcoma. Computed tomographic imaging with contrast and positron emission tomography revealed disseminated disease. She underwent chemotherapy and radiation but died within one year of diagnosis.

Conclusions: The prognosis for patients with angiosarcoma is generally poor, especially with disseminated disease. Early detection remains the key element in maximizing patient outcomes.


Angiosarcoma, vulvar angiosarcoma, sarcoma, melanoma

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The authors report no conflict of interest.


Copyright © 2014 Ashley Lafever, Eric M. Tyler, and Colleen K. Stockdale

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