Evaluation of the efficiency of antibiotic prophylaxis in cesarean cases

Reyhan Kaplan Hafızoğlu, Department of Obstetrics and Gynecology, Sakarya University School of Medicine, Sakarya Research and Education Hospital, Sakarya, Turkey
Serkan Kumbasar, Department of Obstetrics and Gynecology, Sakarya University School of Medicine, Sakarya Research and Education Hospital, Sakarya, Turkey
Bulat Aytek Şık, Faculty of Health Sciences, Aydin University, İstanbul, Turkey
Murat Bozkurt, Department of Obstetrics and Gynecology, Sakarya University School of Medicine, Sakarya Research and Education Hospital, Sakarya, Turkey
Mustafa Ulaş, Department of Physiology, Fırat University School of Medicine, Elazıg, Turkey
Ayse Ender Yumru, Department of Obstetrics and Gynecology, Şişli Hamidiye Etfal Research and Education Hospital, İstanbul, Turkey
Burcu Dinçgez, Department of Obstetrics and Gynecology, Sevket Yılmaz Research and Education Hospital, Bursa, Turkey
Süleyman Salman, Department of Obstetrics and Gynecology, Gaziosmanpasa Taksim Research and Education Hospital, İstanbul, Turkey

Abstract

Background: In recent years the rate of cesarean section has significantly increased .To determine the efficacy of prophylactic antibiotics in reducing infectious morbidity after cesarean section.

Objectives: In our study, we aimed to evaluate the efficiency of prophylactic antibiotic administration by comparing three groups using single, multiple and no prophylactic antibiotic therapy.

Materials and Methods: Our study is a prospective, randomized controlled study including emergent cases, that developed caesarean indication while in active labor, and elective cesarean cases. A total of 90 patients were included in the study, including 30 patients who underwent caesarean delivery and did not undergo an antibiotic prophylaxis (Group 1), 30 patients who underwent a single dose antibiotic prophylaxis (Group II) and 30 patients who underwent multiple dose antibiotic prophylaxis (Group III).

Results: The incidence of wound infection was significantly higher in cases that were not using antibiotics at postoperative days 3, 5 and 7 compared to the cases using single and multiple antibiotics. There was not a significant difference between groups in terms of endometritis.

Conclusion: Administration of prophylactic antibiotics prevent wound infection but does not prevent development of endometritis.

 

URL

http://ir.uiowa.edu/pog_in_press/43