Date of Degree
MS (Master of Science)
Electrical and Computer Engineering
Reinhard R. Beichel
First Committee Member
Second Committee Member
For radiation treatment of cancer and image-based quantitative assessment of treatment response, target structures like tumors and lymph nodes need to be segmented. In current clinical practice, this is done manually, which is time consuming and error-prone. To address this issue, a semi-automated graph-based segmentation approach was developed.
It was validated with 60 real datasets, segmented by two users manually and with this new algorithm, and 44 scans of a phantom dataset. The results showed a statistically significant improvement in intra- and interoperator consistency of segmentations, a statistically significant improvement in speed of segmentation, and reasonable accuracy against consensus images and phantoms. As such, the algorithm can be applied in cases that otherwise would use manual segmentation.
cancer, head, neck, PET, segmentation, tumor
xiii, 99 pages
Includes bibliographical references (pages 98-99).
Copyright © 2014 Markus Lane Van Tol
Van Tol, Markus Lane. "A graph-based method for segmentation of tumors and lymph nodes in volumetric PET images." MS (Master of Science) thesis, University of Iowa, 2014.