Document Type


Date of Degree

Spring 2010

Degree Name

MS (Master of Science)

Degree In

Biomedical Engineering

First Advisor

Goetz, Jessica

Second Advisor

Brown, Thomas D

First Committee Member

Dove, Edwin

Second Committee Member

Reinhardt, Joseph

Third Committee Member

Thedens, Daniel

Fourth Committee Member

Lawler, Ericka


As the incidence of diagnosed carpal tunnel syndrome continues to increase, an understanding of the mechanism(s) of insult to the median nerve which leads to its development becomes ever more imperative. Knowledge of the exact cause of CTS could lead to improved diagnostic and treatment methods, or more importantly, to better preventative measures. The goal of this study was to investigate movements and interactions of structures within the carpal tunnel during wrist flexion and hand loading in order to obtain information about a specific mechanism of insult to the median nerve. Symptomatic and normal subjects were compared to observe differences in the interactions of the median nerve and its surrounding structures. A new methodology was developed to facilitate the evaluation of these populations.


Carpal Tunnel Syndrome, Digital Flexor Tendons, Impingement, Magnetic Resonance Imaging, Median Nerve


xi, 120 pages


Includes bibliographical references (pages 114-120).


Copyright 2010 Nicole Marie Kunze