Breast Cancer – Targets and Therapy
DOI of Published Version
Breast cancer in the elderly is an increasing clinical problem. In addition, ~60% of deaths from breast cancer occur in women aged 65 years and older. Despite this, older women with breast cancer have been underrepresented in clinical trials, and this has led to less than optimal evidence to guide their therapy. The management of elderly women with early breast cancer is a complex process that requires careful evaluation of life expectancy, comorbidities, patient values, and risks and benefits of available treatment options. This review will focus on current adjuvant systemic therapy options for older women with breast cancer, discuss the principles in the decision-making process, and define the role of endocrine therapy, chemotherapy, and targeted agents.
OAfund, breast cancer, adjuvant therapy, chemotherapy, endocrine therapy, elderly
Journal Article Version
Version of Record
Published Article/Book Citation
Breast Cancer – Targets and Therapy. 25 July 2016 Volume 2016:8 Pages 141—147. DOI 10.2147/BCTT.S110765
© 2016 Leone et al.
Creative Commons License
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