Document Type

Article

Peer Reviewed

1

Publication Date

12-12-2016

NLM Title Abbreviation

Neuroimage Clin

Journal/Book/Conference Title

NeuroImage: clinical

DOI of Published Version

https://doi.org/10.1016/j.nicl.2016.12.010

Start Page

370

End Page

377

Total Pages

8

Abstract

Although several studies have demonstrated that facial-affect recognition impairment is common following moderate-severe traumatic brain injury (TBI), and that there are diffuse alterations in large-scale functional brain networks in TBI populations, little is known about the relationship between the two. Here, in a sample of 26 participantswith TBI and 20 healthy comparison participants (HC)wemeasured facial-affect recognition abilities and resting-state functional connectivity (rs-FC) using fMRI. We then used network-based statistics to examine (A) the presence of rs-FC differences between individuals with TBI and HC within the facial-affect processing network, and (B) the association between inter-individual differences in emotion recognition skills and rs-FC within the facial-affect processing network.We found that participants with TBI showed significantly lower rs-FC in a component comprising homotopic and within-hemisphere, anterior-posterior connectionswithin the facial-affect processing network. In addition,within the TBI group, participantswith higher emotion-labeling skills showed stronger rs-FC within a network comprised of intra- and inter-hemispheric bilateral connections. Findings indicate that the ability to successfully recognize facial-affect after TBI is related to rs-FC within components of facial-affective networks, and provide new evidence that further our understanding of the mechanisms underlying emotion recognition impairment in TBI.

Keywords

OAfund, Traumatic brain injury, Emotion recognition, Facial affect, Emotion labeling, Resting state, Network-based statistics

Granting or Sponsoring Agency

NICHD/NCMRR grant R01 HD071089, the University of IowaMagnetic Resonance Research Facilities and a research grant fromthe University of Iowa Graduate and Professional Student Government.

Grant Number

R01 HD071089

Journal Article Version

Version of Record

Published Article/Book Citation

NeuroImage: Clinical 13 (2017) 370–377

http://dx.doi.org/10.1016/j.nicl.2016.12.010 2213-1582

Rights

© 2016 The Authors.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Included in

Neurosciences Commons

Share

COinS
 

URL

https://ir.uiowa.edu/neuroscience_pubs/1