Is job-related stress the link between cardiovascular disease and the law enforcement profession?

Document Type


Peer Reviewed


Publication Date


NLM Title Abbreviation

J Occup Environ Med

Journal/Book/Conference Title

Journal of Occupational & Environmental Medicine

DOI of Published Version



OBJECTIVE: To determine whether job-related stress is associated with alterations in pro- and anti-atherogenic inflammatory mediators among law enforcement officers. METHODS: Markers of vascular inflammation and the self-reported stress measures of perceived stress, vital exhaustion, job strain, effort-reward imbalance, and social support were compared between officers (N = 444) and non-officers (N = 166). RESULTS: Officers had higher levels of IL-1beta, IL-6, IL-10, and TNF-alpha and lower levels of C-reactive protein and fibrinogen. No more than 4% of the variability in any of the inflammatory mediators was explained by any stress measure for either the two groups or the entire sample. CONCLUSIONS: Law enforcement officers may be at an increased risk for cardiovascular disease due to a relatively greater pro-inflammatory vascular environment. However, this increased risk cannot be attributed to either chronic stress or the work-related stress measures assessed here.


Cardiovascular Risk Factors, Police, Stress, Occupational -- Adverse Effects, Adult, C-Reactive Protein, Cardiovascular Diseases -- Epidemiology, Descriptive Statistics, Enzyme-Linked Immunosorbent Assay, Female, Funding Source, Human, Iowa, Male, Metabolic Syndrome X -- Risk Factors, P-Value, Questionnaires, Regression, Scales, Sex Factors, Support, Psychosocial, T-Tests

Published Article/Book Citation

Journal of Occupational & Environmental Medicine, 52:5 (2010) pp.561-565. DOI:10.1097/JOM.0b013e3181dd086b.

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