Stereoselective synthesis of the hormonally active (25S)-delta7-dafachronic acid, (25S)-Delta4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid

Rene' Martin, University of Iowa
F. Dabritz
E. V. Entchev
T. V. Kurzchalia
H. J. Knolker

Abstract

We report a stereoselective synthesis of the (25S)-cholestenoic-26-acids which are highly efficient ligands for the hormonal receptor DAF-12 in Caenorhabditis elegans.

 

URL

https://ir.uiowa.edu/nursing_pubs/921