Title

Culture systems: embryo culture and monozygotic twinning

Document Type

Article

Peer Reviewed

1

Publication Date

1-1-2012

NLM Title Abbreviation

Methods Mol Biol

Journal/Book/Conference Title

Methods in molecular biology (Clifton, N.J.)

PubMed ID

22829386

DOI of Published Version

10.1007/978-1-61779-971-6_22

Start Page

387

End Page

397

Abstract

The incidence of monozygotic twinning in pregnancies achieved with assisted reproductive technologies (ART) is significantly higher than spontaneously conceived pregnancies. The factors associated with ART that predispose the embryos to splitting are not well-characterized. Assisted hatching and extended embryo culture are two ART laboratory methods that have been risk factors for monozygotic twinning. The methods and strategies that may be employed to avoid monozygotic twinning are discussed in this chapter.

Keywords

Blastocyst/metabolism/radiation effects, Embryo Culture Techniques/methods, Embryo, Mammalian/drug effects/embryology/radiation effects, Female, Humans, Laboratories, Lasers, Pregnancy, Reproductive Techniques, Assisted, Single Embryo Transfer, Twinning, Monozygotic

Published Article/Book Citation

Methods in molecular biology (Clifton, N.J.), 912 (2012) pp.387-397.

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URL

https://ir.uiowa.edu/obgyn_pubs/1066