Title

Postoperative irradiation in malignant tumors of submandibular gland

Document Type

Article

Peer Reviewed

1

Publication Date

1-1-1999

NLM Title Abbreviation

Cancer Invest

Journal/Book/Conference Title

Cancer investigation

PubMed ID

10999047

DOI of Published Version

10.1080/07357909909011715

Start Page

36

End Page

38

Abstract

A retrospective review of 18 patients with treated primary malignant tumors of submandibular gland is presented. The data revealed that initial control of malignancies was inversely related to the presence of disease and surgical margins. Postoperative radiation therapy was used in cases with positive surgical margins. Of the patients with inadequate surgical margins, 71% achieved local relapse when they had surgery alone, compared with 27% of the group that received postoperative irradiation. This study suggests that adjuvant radiation therapy may improve the local control and survival. Such therapy can serve as the salvage method for those who have inadequate surgical margins. Re-excision is disappointing in its ability to control this disease.

Keywords

Adenocarcinoma/pathology/radiotherapy/surgery, Adult, Aged, Carcinoma/mortality/pathology/radiotherapy/surgery, Carcinoma, Adenoid Cystic/mortality/pathology/radiotherapy/surgery, Carcinoma, Mucoepidermoid/pathology/radiotherapy/surgery, Carcinoma, Squamous Cell/pathology/radiotherapy/surgery, Combined Modality Therapy, Female, Humans, Male, Middle Aged, Neck Dissection, Neoplasm Recurrence, Local, Postoperative Period, Radiotherapy, Adjuvant, Retrospective Studies, Salvage Therapy, Submandibular Gland Neoplasms/mortality/pathology/radiotherapy/surgery, Survival Analysis, Treatment Outcome

Published Article/Book Citation

Cancer investigation, 17:1 (1999) pp.36-38.

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URL

https://ir.uiowa.edu/obgyn_pubs/226