Patents assigned to the University of Iowa, by faculty and researchers at the University of Iowa.
Submissions from 2018
US Patent 9,856,204 Methods for inhibiting muscle atrophy, Christopher M. Adams, Steven D. Kunkel, Manish Suneja, and Michael Welsh
US Patent 9,891,301 Apparatus and methods for dynamical tracking of mechanical activity within cell populations, Barry London, Vladimir Shusterman, and Xiaodong Zhu
US Patent 9,861,802 Catheters, catheter systems, and methods for puncturing through a tissue structure, Steven Richard Mickelsen
US Patent 9,884,052 Compounds and methods to treat organophosphorus poisoning, Daniel M. Quinn and Joseph John Topczewski
US Patent 9,865,660 Organic magnetoelectroluminescence for transduction between magnetic and optical information, Markus Wohlgenannt, Michael Flatte, Andrew Kent, Fujian Wang, Nicholas Harmon, and Ferran Macia Bros
Submissions from 2017
US Patent 9,545,196 Automated assessment of glaucoma loss from optical coherence tomography, Michael Abramoff and Milan Sonka
US Patent 9,539,367 Gallium inhibits biofilm formation, Bradley E. Britigan and Pradeep K. Singh
US Patent 9,849,195 Methods and compositions for treating brain diseases, Beverly L. Davidson
US Patent 9,650,631 Reduction of off-target RNA interference toxicity, Beverly L. Davidson, Alejandro Mas Monteys, Jodi L. Mcbride, and Ryan Boudreau
US Patent 9,540,659 Modified adeno-associated virus vector compositions, Beverly L. Davidson, Maria Scheel, Ryan Boudreau, and Alejandro Mas Monteys
US Patent 9,806,710 Voltage-controlled magnetic-based devices having topological insulator/magnetic insulator heterostructure, Michael Flatté
US Patent 9,776,017 Method and system for dynamically-trimmed spot scanning for ion therapy, Ryan Flynn, Daniel Hyer, Dongxu Wang, Patrick Hill, and Yves Claereboudt
US Patent 9,624,497 Nucleic acid aptamers, Paloma Giangrande, Francis Miller, and William Thiel
US Patent 9,572,976 System that secures an electrode array to the spinal cord for treating back pain, Matthew A. Howard, Hiroyuki Oya, Steve Viljoen, and Chandan G. Reddy
US Patent 9,595,171 Methods and systems for augmentative and alternative communication, Richard Hurtig, Benjamin Berkowitz, Blake Earl Martinson, Zihan Zhu, and Richard Rives Bird
US Patent 9,730,988 Parasitic biological agents for treatment and prevention of graft versus host disease, Mirac Nedim Ince, David E. Elliott, and George J. Weiner
US Patent 9,669,115 Co-crystals and salts of contrast agents and imaging, Leonard R. Macgillivray
US Patent 9,603,949 Oligonucleotide-based probes for detection of bacterial nucleases, James O. Mcnamara II, Katie R. Stockdale, Lingyan Huang, Alexander R. Horswill, Mark A. Behlke, and Frank J. Hernandez
US Patent 9,724,170 Catheters, catheter systems, and methods for puncturing through a tissue structure and ablating a tissue region, Steven Richard Mickelsen
US Patent 9,572,894 Biodegradable particulate formulations, Aliasger K. Salem, Sean M. Geary, George J. Weiner, Caitlin Lemke, and Yogita Krishnamachari
US Patent 9,758,781 Methods to prevent and treat autosomal dominant non-syndromic hearing loss, Richard J. H. Smith and Seiji Shibata
US Patent 9,649,357 Treatment of chronic nephropathies using soluble complement receptor type I (sCR1), Richard J. H. Smith, Yuzhou Zhang, and Henry C. Marsh
US Patent 9,801,922 Compositions and methods of treating cancer, Douglas R. Spitz, Michael K. Schultz, Kyle Kloepping, Yueming Zhu, Nukhet Aykin-burns, and Max S. Wicha
US Patent 9,611,301 GB virus C (hepatitis G virus) E2 glycoprotein as an immunomodulatory agent, Jack T. Stapleton, Nirjal Bhattarai, Jinhua Xiang, and James H. Mclinden
US Patent 9,750,516 Positioning device for ankle joint replacement surgery, Yuki Tochigi, Thomas E. Baer, and Charles L. Saltzman
US Patent 9,820,651 Methods and devices for labeling and/or matching, Juerg Tschirren, Milan Sonka, Joseph Reinhardt, Geoffrey Mclennan, and Eric Hoffman
US Patent 9,661,831 Transgenic pig models of cystic fibrosis, Michael J. Welsh and David A. Stoltz
US Patent 9,745,331 Therapeutic bisphosphonates, David Wiemer
US Patent 9,828,587 Chimeric adeno-associated virus/ bocavirus parvovirus vector, Ziying Yan, John F. Engelhardt, and Jianming Qiu
Submissions from 2016
US Patent 9,254,295 Tomatidine, analogs thereof, compositions comprising same, and uses for same, Christopher M. Adams, Michael C. Dyle, and Michael Welsh
US Patent 9,295,664 Methods for lowering blood glucose, Christopher M. Adams, Steven D. Kunkel, and Michael Welsh
US Patent 9,422,248 Phenyl- and pyridinyl-substituted 2,2,2-trifluoroethanols having anticonvulsant properties, Max T. Baker and Rajesh K. Mishra
US Patent 9,345,776 Biodegradable polymers with sulfenamide bonds for drug delivery applications, Ned B. Bowden, Denison J. Kuruvilla, Aliasger K. Salem, and Jun Yoo
US Patent 9,387,210 Inhibitors of phosphodiesterase type 5A for treating or preventing muscle disease or the symptoms thereof in a patient, Kevin P. Campbell, Yvonne M. Kobayashi, and Robert W. Crawford
US Patent 9,238,040 Chemoprevention of colorectal cancer by mesalamine/sulfasalazine, Kiron M. Das and Jim Jung-ching Lin
US Patent 9,523,093 Huntington's disease therapeutic compounds, Beverly L. Davidson and Alejandro Mas Monteys
US Patent 9,487,779 siRNA-mediated gene silencing, Beverly L. Davidson, Henry Paulson, Victor Miller, and Cynthia Gouvion
US Patent 9,260,716 RNA interference suppression of neurodegenerative diseases and methods of use thereof, Beverly L. Davidson, Haibin Xia, Qinwen Mao, Henry Paulson, Ryan Boudreau, and Scott Harper
US Patent 9,388,410 Alternative export pathways for vector expressed RNA interference, Scott Harper and Beverly L. Davidson
US Patent 9,435,721 Isolation and characterization of tumor cells using shear stress measurements, Michael D. Henry and Matthew J. Barnes
US Patent 9,416,149 Methods to modulate Rac1 import and to treat pulmonary fibrosis, Raymond J. Hohl and Brent A. Carter
US Patent 9,403,008 Managing back pain by applying a high frequency electrical stimulus directly to the spinal cord, Matthew A. Howard
US Patent 9,254,379 System that secures an electrode array to the spinal cord for treating back pain, Matthew A. Howard, Hiroyuki Oya, Steve Viljoen, and Chandan G. Reddy
US Patent 9,364,660 Electrode array device configured for placement inside the dura for direct spinal cord stimulation, Matthew Howard, Timothy Brennan, Brian Dalm, Marcel Utz, George T. Gillies, Steven Scott, Randall S. Nelson, and Robert Shurig
US Patent 9,486,621 Implanting an electrode array against the spinal cord inside the dura for stimulating the spinal cord and treating pain, Matthew Howard, Timothy Brennan, Brian Dalm, Marcel Utz, George T. Gillies, Steven Scott, Randall S. Nelson, and Robert Shurig
US Patent 9,346,781 Therapeutic compounds, Zhendong Jin and Lei Chen
US Patent 9,428,493 Schweinfurthin analogues, John Kodet, Jeffrey D. Neighbors, and David F. Wiemer
US Patent 9,370,529 Tannin inhibitors of HIV, George A. Kraus and Wendy Maury
US Patent 9,506,085 Ammonia production using bioelectrocatalytical devices, Johna Leddy and Timothy Michael Paschkewitz
US Patent 9,272,016 Methods to enhance RNAi oligonucleotide delivery to respiratory epithelial cells, Paul B. Mccray Jr., Beverly L. Davidson, and Sateesh Krishnamurthy
US Patent 9,506,843 Personal nanoparticle respiratory depositions sampler and methods of using the same, Thomas Peters and Lorenzo Cena
US Patent 9,428,494 Therapeutic compounds, Thomas Prisinzano
US Patent 9,249,100 Compounds and methods to treat organophosphorus poisoning, Daniel M. Quinn and Joseph John Topczewski
US Patent 9,295,713 Treatment of chronic nephropathies using soluble complement receptor type I (sCR1), Richard J. H. Smith, Yuzhou Zhang, and Henry C. Marsh
US Patent 9,274,429 Method for producing layered materials using long-lived photo-induced active centers, Cynthia G. Templeman, Alec B. Scranton, Beth Ann Rundlett, and Cynthia Hoppe
Submissions from 2015
US Patent 9,063,139 Variants in complement regulatory genes predict age-related macular degeneration, Rando L. Allikmets, Gregory S. Hageman, Michael C. Dean, and Albert M. Gold
US Patent 9,168,307 Mitochondrial-targeted cationic nanoparticles comprising CaMKII inhibitors and uses thereof for treating and preventing diseases and disorders associated with CaMKII activity, Mark E. Anderson, Mei-ling A. Joiner, Aliasger K. Salem, Amaraporn Wongrakpanich, Frederick E. Domann, Duane D. Hall, Olha M. Koval, and Douglas R. Spitz
US Patent 9,090,701 Methods of detecting oxidized calcium/calmodulin dependent protein kinase II, Mark E. Anderson, Peter J. Mohler, Douglas R. Spitz Jr., and Jeffrey Robert Erickson
US Patent 8,981,012 Modified polydicyclopentadienes, Ned B. Bowden and Mathew Perring
US Patent 9,193,777 Method of treating cardiac arrhythmia with long acting atrial natriuretic peptide(LA-ANP), John C. Burnett Jr., Timothy M. Olson, Leonid V. Zingman, and Denice Marie Hodgson-zingman
US Patent 9,181,544 Therapeutic compounds, Beverly L. Davidson and Ryan L. Boudreau
US Patent 9,169,483 RNA interference suppression of neurodegenerative diseases and methods of use thereof, Beverly L. Davidson, Alejandro Mas Monteys, and Ryan L. Boudreau
US Patent 9,125,967 Fluorapatite glass-ceramics, Isabelle Denry and Julie Holloway
US Patent 9,119,957 Cochlear implant system component having multiple electrode assemblies, Bruce J. Gantz, James Finlay Patrick, and John L. Parker
US Patent 9,163,242 HER2 nucleic acid aptamers, Paloma H. Giangrande, James O. Mcnamara, Kristina W. Thiel, William Thiel, and William M. Rockey
US Patent 9,139,835 Nucleic acid aptamers, Paloma Giangrande, Francis Miller, and William Thiel
US Patent 9,063,118 Isolation and characterization of tumor cells using shear stress measurements, Michael D. Henry and Matthew J. Barnes
US Patent 9,056,005 Methods and devices for arytenoid repositioning, Henry T. Hoffman
US Patent 9,181,291 Tannin inhibitors of HIV, George A. Kraus and Wendy Maury
US Patent 9,050,264 Cellulose capsules and methods for making them, Vijay Kumar and Bhavik Bhatt
US Patent 8,951,498 Synthesis of hierarchical nanocrystalline zeolites with controlled particle size and mesoporosity, Sarah Larsen and Anton Petushkov
US Patent 8,940,510 Spray dried microbes and methods of preparation and use, Venkiteswaran Subramanian, James H. Glenn IV, and Shuvendu Das
US Patent 8,951,752 N-demethyase genes and uses thereof, Venkiteswaran Subramanian, Michael Tai-man Louie, and Ryan Summers
US Patent 8,993,042 Method for determining the production parameters for a substrate coating process, Cynthia Gazepis Templeman, Alec B. Scranton, Beth Ann Ficek, and Cynthia Hoppe
US Patent 9,211,347 Method of delivering vectors to pancreas and lungs by cannulating the aorta, Aliye Uc, Paul B. Mccray, Beverly L. Davidson, and Abhay Divekar
US Patent 9,192,633 Use of parasitic biological agents for disease prevention and control, Joel V. Weinstock and David E. Elliott
Submissions from 2014
US Patent 8,794,230 Articulated oral airway, Ron Owen Abrons
US Patent 8,841,423 Monoclonal antibodies specific for oxidized calcium/calmodulin dependent protein kinase II, Mark E. Anderson, Peter J. Mohler, Douglas R. Spitz Jr., and Jeffrey Robert Erickson
US Patent 8,778,186 High-density polydicyclopentadiene, Ned B. Bowden, Abhinaba Gupta, and Tyler R. Long
US Patent 8,921,447 Photo-enforced stratification of polymeric materials, Clinton J. Cook and Allan C. Guymon
US Patent 8,691,948 Methods and compositions for treating brain diseases, Beverly L. Davidson and Yong Hong Chen
US Patent 8,779,116 SiRNA-mediated gene silencing, Beverly L. Davidson, Henry Paulson, Victor Miller, and Cynthia Gouvion
US Patent 8,846,030 Compounds and methods to enhance rAAV transduction, John F. Engelhardt and Dongsheng Duan
US Patent 8,630,721 Hybrid cochlear implant, Bruce J. Gantz
US Patent 8,685,937 Nucleic acid aptamers, Paloma H. Giangrande, James O. Mcnamara, and Anton P. Mccaffrey
US Patent 8,691,567 Alternative export pathways for vector expressed RNA interference, Scott Harper and Beverly L. Davidson
US Patent 8,834,900 Combination motif immune stimulatory oligonucleotides with improved activity, Arthur M. Krieg and Jorg Vollmer
US Patent 8,846,578 Zinc finger nuclease for the CFTR gene and methods of use thereof, Paul Mccray, Morgan Maeder, and Jae Keith Joung
US Patent 8,703,469 Baculoviruses with enhanced virion production and a method for the production of baculoviruses, Paul Mccray, Patrick Sinn, and Gary Blissard
US Patent 8,621,701 Dental brush assembly and method for making the same, Michael R. Meharry
US Patent 8,680,641 System and method of planar processing of semiconductors into detector arrays, John P. Prineas, Jonathan T. Olesberg, and Chris Coretsopoulos
US Patent 8,758,387 Biofeedback training of anal and rectal muscles, Satish Sanku Chander Rao and Muralidhar Nukala Sunil Kumar
US Patent 8,686,016 Schweinfurthins and uses thereof, Karlyne Reilly, Thomas Turbyville, John A. Beutler, and David Wiemer
US Patent 8,858,946 Method for inhibiting HIV-1 replication utilizing anti-GBV-C E2 antibodies, Jack T. Stapleton, Jinhua Xiang, Donna Klinzman, and James H. Mclinden
US Patent 8,636,744 Positioning device for ankle joint replacement surgery, Yuki Tochigi, Thomas E. Baer, and Charles L. Saltzman
US Patent 8,676,302 Systems and methods for multi-spectral bioluminescence tomography, Ge Wang, Alexander Cong X, Weimin Han, Ming Jiang, Haiou Shen, and Wenxiang Cong
US Patent 8,912,386 Transgenic pig model of cystic fibrosis, Michael J. Welsh, Christopher S. Rogers, Randall S. Prather, John Engelhardt, and Ziying Yan
US Patent 8,637,685 Schweinfurthin analogues, David F. Wiemer, Jeffrey D. Neighbors, Raymond J. Hohl, and Craig Kuder
Submissions from 2013
US Patent 8,616,702 Hybrid laser ophthalmoscope, Michael Abrámoff
US Patent 8,440,656 Methods of treating pulmonary diseases and disorders by modulating calcium/calmodulin dependent protein kinase II activity, Mark E. Anderson, Isabella M. Grumbach, and Joel N. Kline