US Patent 5,187,063
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The invention pertains to the dystrophin-glycoprotein complex of mammalian skeletal muscle and a method of isolating said complex. The components of the complex and methods of separating and isolating said components also pertain to the invention. In addition, the invention further relates to a method of diagnosing muscular dystrophy by detecting and quantifying the loss of a non-dystrophin component of the dystrophin-glycoprotein complex with said loss being indicative of muscular dystrophy.
Campbell, Kevin P.; Ervasti, James M.; Ohlendieck, Kay; Gaver, Mitchell G.; and Kahl, Steven D. Measuring non-dystrophin proteins and diagnosing muscular dystrophy. US Patent 5,187,063 filed May 23, 1990 and issued February 16, 1993. https://ir.uiowa.edu/patents/102