US Patent 5,225,424
United States Patent and Trademark Office
University of Iowa Research Foundation (Oakdale, IA, US)
N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)ylidene] -2-acetyloxyacetamide, commonly referred to as acetylhydroxymethazolamide and is a water soluble pharmacologically active carbonic anhydrase inhibitor.
Schoenwald, Ronald D. and Barfknecht, Charles F. Methazolamide-derived carbonic anhydrase inhibitors. US Patent 5,225,424 filed October 21, 1992 and issued July 06, 1993. https://ir.uiowa.edu/patents/105