Document Type

Patent

Patent Number

US Patent 5,234,922

Patent agency

United States Patent and Trademark Office

Publication Date

8-10-1993

Assignee

University of Iowa Research Foundation (Oakdale, IA, US)

Application Number

07/952,279

Date Filed

1992-09-28

Total Pages

7 pages

Abstract

Methods for the treatment of secretory diarrhea comprised of administering to a patient in need thereof, an effective amount of a CFTR chloride channel blocker or a potassium channel opener are disclosed. The CFTR chloride channel blocker is a sulfonylurea of the group consisting of tolbutamide, glibenclamide, and related analogs. The potassium channel opener is selected from the group consisting of diazoxide, lemakalim, and minoxidil sulfate.

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URL

https://ir.uiowa.edu/patents/108