US Patent 5,256,698
United States Patent and Trademark Office
University of Iowa Research Foundation (Oakdale, IA, US)
The method and composition for treating psychotic disorders with psychoactive drugs which bind at the sigma binding site and act as antagonists to inhibiting psychotic action. The preferred compounds are N-cyclohexyl-N-ethyl benzylamine, N-cyclohexyl-N-ethyl 2-phenylethylamine, and bromhexine.
Schoenwald, Ronald D.; Barfknecht, Charles F.; and Newton, Roger E. Treatment of psychosis using cyclohexyl-phenyl-lower alkyl amine derivatives. US Patent 5,256,698 filed July 24, 1990 and issued October 26, 1993. https://ir.uiowa.edu/patents/110