Document Type

Patent

Patent Number

US Patent 5,403,711

Patent agency

United States Patent and Trademark Office

Publication Date

4-4-1995

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

08/088,622

Date Filed

1993-07-06

Total Pages

20 pages

Abstract

A method of detection of nucleic acid (DNA or RNA) target sequence in which such a sequence serves as a cofactor for a catalytic reaction in which a complementary, labeled nucleic acid probe is cleaved such that the target sequence is released intact and can repeatedly recycle through the reaction pathway, thereby providing signal amplification.

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URL

https://ir.uiowa.edu/patents/133