Document Type

Patent

Patent Number

US Patent 5,418,139

Patent agency

United States Patent and Trademark Office

Publication Date

5-23-1995

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

08/016,126

Date Filed

1993-02-10

Total Pages

6 pages

Abstract

Disclosed herein are methods for screening for primary cardiomyopathy. The methods are preferably immunological methods in which the level of binding of a monoclonal or polyclonal antibody to a 50 kD glycoprotein component of a mammalian muscle tissue is determined. This level of binding is compared to the level of binding observed when non-dystrophic tissue is treated in an otherwise identical manner. A substantial reduction in the level of binding to the 50 kD glycoprotein in the experimental mammalian muscle tissue has been determined to be a screen for primary cardiomyopathy.

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URL

https://ir.uiowa.edu/patents/136