US Patent 5,430,129
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The invention pertains to pure, native dystrophin of mammalian skeletal muscle and a method of purifying dystrophin from mammalian skeletal muscle. The invention further pertains to a method of diagnosing muscular dystrophy by detecting the loss or abnormal structure of pure, native dystrophin from mammalian skeletal muscle. The detection of a loss of dystrophin or an abnormal structure of dystrophin is indicative of muscular dystrophy.
Campbell, Kevin P.; Kahl, Steven D.; and Ervasti, James M. Purified, native dystrophin. US Patent 5,430,129 filed January 16, 1991 and issued July 04, 1995. https://ir.uiowa.edu/patents/137