Document Type

Patent

Patent Number

US Patent 4,147,691

Patent agency

United States Patent and Trademark Office

Publication Date

4-3-1979

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

05/783,511

Date Filed

1977-03-31

Total Pages

6 pages

Abstract

Pure cesalin having a high degree of anti-tumor activity is obtained by organic solvent extraction of either the whole seeds or the endosperm of the plant Caesalpinia gilliesii, to remove a lipid portion, extraction of the defatted endosperm with water, dialysis of the extract against water, separation of the non-dialyzable portion into a supernatant, precipitating crude cesalin from the supernatant by acidification or with ammonium sulfate, and purifying the crude cesalin by gel filtration and elution.

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URL

https://ir.uiowa.edu/patents/15