US Patent 5,565,434
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
A method of reducing intraocular eye pressure by topically applying to an affected eye a small but therapeutically effective intraocular eye pressure reducing amount of a compound which is a 2-deoxyglucose or hexose or pentose derivative of ethacrynic acid.
Barfknecht, Charles F. and Schoenwald, Ronald D. Hexose and pentose prodrugs of ethacrynic acid. US Patent 5,565,434 filed February 23, 1996 and issued October 15, 1996. https://ir.uiowa.edu/patents/153