Document Type

Patent

Patent Number

US Patent 5,591,872

Patent agency

United States Patent and Trademark Office

Publication Date

1-7-1997

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

08/104,487

Date Filed

1993-08-09

Total Pages

13 pages

Abstract

Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, for Pseudomonas aeruginosa are described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the autoinducer molecules also are described. The molecules are useful for treating or preventing infection by Pseudomonas aeruginosa.

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URL

https://ir.uiowa.edu/patents/159