US Patent 5,766,943
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
This invention discloses the isolation and purification of gene sequences which code upon expression a soluble form of the traditionally membrane bound immuno-regulatory protein, CD23. This protein regulates the amount of IgE present in the blood and upon cloning and amplification, procedures may be used in the treatment of IgE mediated diseases.
Lynch, Richard G.; Yodoi, Junji; Nunez, Rafael M.; and Matsui, Minoru DNA sequences for soluble form of CD23. US Patent 5,766,943 filed December 28, 1994 and issued June 16, 1998. https://ir.uiowa.edu/patents/185