Document Type

Patent

Patent Number

US Patent 6,057,288

Patent agency

United States Patent and Trademark Office

Publication Date

5-2-2000

Assignee

University of Iowa (Iowa City, IA, US) ; University of Rochester (Rochester, NY, US) ; Ithaca College (Ithaca, NY, US)

Application Number

08/456,864

Date Filed

1995-06-01

Total Pages

12 pages

Abstract

Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, for Pseudomonas aeruginosa are described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the autoinducer molecules also are described. The molecules are useful for treating or preventing infection by Pseudomonas aeruginosa.

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URL

https://ir.uiowa.edu/patents/236