Document Type

Patent

Patent Number

US Patent 6,171,813

Patent agency

United States Patent and Trademark Office

Publication Date

1-9-2001

Assignee

BioTechnology Research & Develop. Corp. (Peoria, IL) ; University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

08/951,506

Date Filed

1997-10-16

Total Pages

18 pages

Abstract

A method is presented for catalyzing the conversion of substrate into product in an organic reaction solvent with an enzyme-surfactant ion pair. The enzyme-surfactant ion pair comprises the enzyme catalyzing the reaction and a surfactant capable of forming an ion pair with the enzyme. Water present in the organic solvent at a concentration of about 0.03% to about 2.5% is sufficient to enhance the rate of catalysis and stabilize the enzyme without substantially increasing the rate of hydrolysis when compared to the anhydrous enzyme.

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URL

https://ir.uiowa.edu/patents/253