Document Type

Patent

Patent Number

US Patent 4,303,419

Patent agency

United States Patent and Trademark Office

Publication Date

12-1-1981

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

06/166,382

Date Filed

1980-07-07

Total Pages

6 pages

Abstract

N-nitrosamines are reacted with a denitrosating agent to cleave the N-NO bond and yield nitric oxide which may be analyzed to determine both qualitatively and quantitatively, the N-nitrosamine content of a test sample. The denitrosating reagent has the advantage of being useful, even in the presence of substantial amounts of water, and comprises a mixture of glacial acetic acid and a concentrated inorganic acid which is either phosphoric acid or sulfuric acid. The volume ratio of glacial acetic to concentrated acid is within the ratio of from 1:2 to 5:1. This acid component mixture is combined with from about 0.1% to about 5% by weight of soluble inorganic bromide or iodide salt.

Share

COinS
 

URL

https://ir.uiowa.edu/patents/26