Document Type

Patent

Patent Number

US Patent 6,376,662

Patent agency

United States Patent and Trademark Office

Publication Date

4-23-2002

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/142,937

Date Filed

1998-11-17

Total Pages

13 pages

Abstract

A method for synthesizing C-glycosides of ulosonic acids such as Neu5Ac, by which diastereocontrolled synthesis of α-C-glycosides of ulosonic acids is attained is disclosed. In the method of the present invention, an ulosonic acid sulfone or phosphite is reacted with an aldehyde or ketone compound in the presence of a lanthanide metal halide.

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URL

https://ir.uiowa.edu/patents/301