Document Type

Patent

Patent Number

US Patent 6,406,705

Patent agency

United States Patent and Trademark Office

Publication Date

6-18-2002

Assignee

University of Iowa Research Foundation (Iowa City, IA, US) ; Coley Pharmaceutical GmbH (Langenfield, DE) ; Ottawa Health Research Institute (Ottawa, CA)

Application Number

09/325,193

Date Filed

1999-06-03

Total Pages

53 pages

Abstract

The present invention relates generally to adjuvants, and in particular to methods and products utilizing a synergistic combination of immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) and a non-nucleic acid adjuvant. Such combinations of adjuvants may be used with an antigen or alone. The present invention also relates to methods and products utilizing immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) for induction of cellular immunity in infants.

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URL

https://ir.uiowa.edu/patents/307