Document Type

Patent

Patent Number

US Patent 6,479,504

Patent agency

United States Patent and Trademark Office

Publication Date

11-12-2002

Assignee

University of Iowa Research Foundation (Iowa City, IA, US) ; Georgia State University Research Foundation, Inc. (Atlanta, GA) ; The United States of America as represented by the Department of Veterans Affairs (Washington, DC)

Application Number

09/595,875

Date Filed

2000-06-16

Total Pages

73 pages

Abstract

The present invention relates generally to the field of immunology. More particularly it concerns compositions and methods for inhibiting stimulation of the immune system. The compounds and methods comprise compounds that are analogs and derivatives of chloroquine, such as 4-aminoquinolines, and other weak bases. They can be used in preventative and therapeutic treatments of autoimmune diseases and phenomena, transplant rejection such as host-versus-graft disease, and sepsis.

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URL

https://ir.uiowa.edu/patents/317