Document Type

Patent

Patent Number

US Patent 6,528,066

Patent agency

United States Patent and Trademark Office

Publication Date

3-4-2003

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/661,596

Date Filed

2000-09-14

Total Pages

99 pages

Abstract

The present invention provides methods directed to detecting antibodies that specifically bind to a varicella zoster polypeptide, detecting the presence of a varicella zoster virus in an animal, diagnosing a disease caused by varicella zoster virus, and detecting a varicella zoster virus having a single nucleotide polymorphism in ORF68. The present invention also provides a vaccine composition, a method for producing a modified attenuated varicella zoster virus, isolated polynucleotides, and isolated polypeptides, and viruses.

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URL

https://ir.uiowa.edu/patents/325