Document Type

Patent

Patent Number

US Patent 6,653,292

Patent agency

United States Patent and Trademark Office

Publication Date

11-25-2003

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/337,619

Date Filed

1999-06-21

Total Pages

72 pages

Abstract

Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

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URL

https://ir.uiowa.edu/patents/346