Document Type

Patent

Patent Number

US Patent 6,720,151

Patent agency

United States Patent and Trademark Office

Publication Date

4-13-2004

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

10/237,967

Date Filed

2002-09-10

Total Pages

6 pages

Abstract

A gene previously identified in the context of controlling filamentous growth in C. albicans, TUP1, plays a central role in the regulation of phenotype switching in Candida cells. Accordingly, compounds and therapeutic protocols can be screened for an ability to disrupt the pathway, controlled by TUP1, that is comprised of genes the expression of which affect switching specifically. Agents thus identified are candidates for use in treating or preventing candidiasis.

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URL

https://ir.uiowa.edu/patents/352