Document Type

Patent

Patent Number

US Patent 6,723,321

Patent agency

United States Patent and Trademark Office

Publication Date

4-20-2004

Assignee

The Board of Trustees of the University of Illinois (Urbana, IL) ; University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/227,488

Date Filed

1999-01-06

Total Pages

17 pages

Abstract

Provided are compositions and methods useful for modulating the activity of autoinducer synthase catalysts. A method for identifing modulators of the autoinducer synthesis reaction is also provided. Such modulators are useful for controlling bacterial growth and can be used for therapeutic treatment of bacterial infections particularly in immunocompromised subjects. They are also useful in treating disease states associated with autoinducer synthesis and biofilm development.

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URL

https://ir.uiowa.edu/patents/353