Document Type

Patent

Patent Number

US Patent 6,803,191

Patent agency

United States Patent and Trademark Office

Publication Date

10-12-2004

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/424,951

Date Filed

2000-01-20

Total Pages

28 pages

Abstract

A Candida albicans gene, CaNik1, is involved in phenotypic switching which is significant because of a direct correlation between the switching and the level of virulence of the organism. A method of screening for anti-fungal pharmaceutical candidates entails bringing a test substance into contact with cells containing a CaNik1 gene or a variant thereof and then monitoring the effect, if any, on the level of expression of the gene.

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URL

https://ir.uiowa.edu/patents/362