Document Type

Patent

Patent Number

US Patent 6,809,181

Patent agency

United States Patent and Trademark Office

Publication Date

10-26-2004

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/872,852

Date Filed

2001-06-01

Total Pages

46 pages

Abstract

The present invention relates a novel antimicrobial peptide HBD-3 and derivatives thereof as well as the gene encoding the peptide. The invention further relates to methods of use of the HBD-3 peptide including a method of inhibiting microbial growth by administering an effective amount of the HBD-3 peptide alone or in combinination with other antimicrobial agents or antibiotics. In addition, the immunomodulatory properties of the HBD-3 peptide also facilitate the manipulation of the immune response, i.e., as a chemoattractant for immature dentritic cells or memory T cells.

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URL

https://ir.uiowa.edu/patents/363