Document Type

Patent

Patent Number

US Patent 6,855,513

Patent agency

United States Patent and Trademark Office

Publication Date

2-15-2005

Assignee

University of Iowa Research Foundation (Iowa City, IA, US) ; Vertex Pharmaceuticals (San Diego) LLC (San Diego, CA, US)

Application Number

09/653,730

Date Filed

2000-09-01

Total Pages

72 pages

Abstract

The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention provides quorum sensing controlled genetic loci in Pseudomas aeruginosa. Novel indicator strains and vectors for engineering the strains for use in the method of the invention are also provided.

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URL

https://ir.uiowa.edu/patents/371