Document Type

Patent

Patent Number

US Patent 6,897,045

Patent agency

United States Patent and Trademark Office

Publication Date

5-24-2005

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

10/054,665

Date Filed

2002-01-22

Total Pages

78 pages

Abstract

The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.

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URL

https://ir.uiowa.edu/patents/377